| New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus | |
| Pan, Zhenghong1; Ning, Desheng1; Wu, Xingde2; Huang, Sisi1; Li, Dianpeng1; Lv, Shihong1; Pan,ZH (reprint author),Chinese Acad Sci,Guangxi Inst Bot,Guangxi Key Lab Funct Phytochem Res & Utilizat,Guilin 541006,Peoples R China.; pan7260@126.com | |
| 2015-03-15 | |
| 发表期刊 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 卷号 | 25期号:6页码:1329-1332 |
| 摘要 | Three new nor-clerodane diterpenoids, crotoeurins A-C (1-3), together with four known ones were isolated from the twigs and leaves of Croton euryphyllus. Among them, crotoeurin A (1) is a new nor-clerodane diterpenoid dimer with a unique cyclobutane ring via a [2+2] cycloaddition. Their structures were elucidated by spectroscopic analyses and the stereochemistry of 1 was confirmed by single-crystal X-ray diffraction analysis. Compounds 1-3 exhibited neurite outgrowth-promoting activity on NGF-mediated PC12 cells at concentration of 10 mu M. (C) 2015 Elsevier Ltd. All rights reserved. |
| 关键词 | Croton Euryphyllus Crotoeurins A-c Nor-clerodane Diterpenoid Neurite Outgrowth-promoting Activity |
| 学科领域 | Chemistry, Medicinal ; Chemistry, Organic |
| DOI | 10.1016/j.bmcl.2015.01.033 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000350696000032 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/20601 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Pan,ZH (reprint author),Chinese Acad Sci,Guangxi Inst Bot,Guangxi Key Lab Funct Phytochem Res & Utilizat,Guilin 541006,Peoples R China.; pan7260@126.com |
| 作者单位 | 1.Chinese Acad Sci, Guangxi Inst Bot, Guangxi Key Lab Funct Phytochem Res & Utilizat, Guilin 541006, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Pan, Zhenghong,Ning, Desheng,Wu, Xingde,et al. New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2015,25(6):1329-1332. |
| APA | Pan, Zhenghong.,Ning, Desheng.,Wu, Xingde.,Huang, Sisi.,Li, Dianpeng.,...&pan7260@126.com.(2015).New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,25(6),1329-1332. |
| MLA | Pan, Zhenghong,et al."New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 25.6(2015):1329-1332. |
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