中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Isolation and identification of renoprotective substances from the mushroom Ganoderma lucidum
作者: Luo, Qi1, 2; Wang, Xin-Long1; Di, Lei1; Yan, Yong-Ming1, 2; Lu, Qing1; Yang, Xiao-Hua1; Hu, Dong-Bao1; null(程永现)1
刊名: TETRAHEDRON
关键词: Ganoderma lucidum ; Meroterpenoids ; Renoprotective
英文摘要: The fruiting bodies of Ganoderma lucidum have been used in China for the prevention of a wide range of diseases including diabetic nephropathy. Our current investigation with this mushroom led to the isolation of six new and two known phenolic meroterpenoids. The structures and absolute configurations at all stereogenic centers in these substances were assigned by using spectroscopic and computational methods. The new meroterpenoids, chizhines A-F (1-6), are isolated as racemic mixtures. Chiral HPLC was utilized to obtain the individual (-)- and (+)-antipodes of these substances. The renoprotective effects of the selected members of the series, were evaluated by using the ELISA technique and high-glucose-induced rat mesangial cells. The results show that the individual enantiomers of these substances significantly inhibit monocyte chemotactic protein 1 (MCP-1) and fibronectin production in a dose-dependent manner. (C) 2014 Elsevier Ltd. All rights reserved.
出版日期: 2015-02-04
卷号: 71, 期号:5, 页码:840-845
DOI标识: 10.1016/j.tet.2014.12.052
语种: 英语
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20595
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Luo-2015-Isolation and identification of renop.pdf(1113KB)----开放获取View Download

作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Luo, Qi]'s Articles
[Wang, Xin-Long]'s Articles
[Di, Lei]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Luo, Qi]‘s Articles
[Wang, Xin-Long]‘s Articles
[Di, Lei]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Luo-2015-Isolation and identification of renop.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace