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题名: New Meroterpenoids from the Endophytic Fungus Aspergillus flavipes AIL8 Derived from the Mangrove Plant Acanthus ilicifolius
作者: Bai, Zhi-Qiang; Lin, Xiuping; Wang, Junfeng; Zhou, Xuefeng; Liu, Juan; Yang, Bin; Yang, Xianwen; Liao, Shengrong; Wang, Lishu; Liu, Yonghong
刊名: MARINE DRUGS
出版日期: 2015
卷号: 13, 期号:1, 页码:237-248
关键词: meroterpenoid ; Aspergillus flavipes ; endophytic fungus
学科分类: Chemistry, Medicinal
DOI: 10.3390/md13010237
通讯作者: Liu,YH (reprint author),Chinese Acad Sci,Key Lab Trop Marine Bioresources & Ecol,Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine Microbiol,South China Sea Inst Oc,Guangzhou 510301,Guangdong,Peoples R China. ; baizhiqiang10@mails.ucas.ac.cn ; xiupinglin@hotmail.com ; Junfeng1982a@163.com ; xfzhou@scsio.ac.cn ; ljuan2010@qq.com ; bingo525@163.com ; xwyang@scsio.ac.cn ; ljrss@126.com ; wls6856@163.com ; yonghongliu@scsio.ac.cn
文章类型: Article
英文摘要: Four new meroterpenoids (2-5), along with three known analogues (1, 6, and 7) were isolated from mangrove plant Acanthus ilicifolius derived endophytic fungus Aspergillus flavipes. The structures of these compounds were elucidated by NMR and MS analysis, the configurations were assigned by CD data, and the stereochemistry of 1 was confirmed by X-ray crystallography analysis. A possible biogenetic pathway of compounds 1-7 was also proposed. All compounds were evaluated for antibacterial and cytotoxic activities.
类目[WOS]: Chemistry, Medicinal
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: ALTERNARIA-ALTERNATA ; TRICYCLOALTERNARENE DERIVATIVES ; MIXED TERPENOIDS ; PEPTIDE DEFORMYLASE ; INHIBITORY-ACTIVITY ; ASPOCHALASIN ; BICYCLOALTERNARENES ; PRODUCTS ; STRAIN ; TOXINS
收录类别: SCI
项目资助者: National Key Basic Research Program of China (973)'s Project [2011CB915503] ; National High Technology Research and Development Program (863 Program) [2012AA092104] ; National Natural Science Foundation of China [31270402, 20902094, 41176148, 21002110] ; Strategic Leading Science and Technology Project of Chinese Academy of Sciences [XDA11030403] ; Guangdong Marine Economic Development and Innovation of Regional Demonstration Project [GD2012-D01-001]
语种: 英语
WOS记录号: WOS:000348403200013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20574
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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