Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens
Liu, Xu1; Zhan, Rui2; Wang, Wei Guang2; Du, Xue2; Li, Yan2; Zhang, Peng1; Pu, Jian Xin2; Wu, Ji Zhou1; Sun, Han Dong2
AbstractThree rare and new 11,20-epoxy-ent-kaurane diterpenoids, named jianshirubesins D-F (1-3), along with one known analogue (4), were isolated from the aerial parts of Isodon rubescens. Their structures were established by analysis of spectroscopic data. Found in the MTT assay to evaluate the cytotoxicity of compounds 1, 2, and 4, only 1 could selectively inhibit certain cell lines from proliferating. In addition, a simple structure-activity relationship discussion might suggest a new bioactive moiety, different from the alpha,beta-unsaturated ketone group.
KeywordJianshirubesins D-f Isodon Rubescens 11 Cytotoxicity 20-epoxy-ent-kauranoids
Indexed BySCI
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000312772900012
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Huazhong Univ Sci & Technol, Hubei Key Lab Nat Med Chem & Resource Evaluat, Tongji Sch Pharm, Wuhan 430030, Hubei, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Liu, Xu,Zhan, Rui,Wang, Wei Guang,et al. Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens[J]. ARCHIVES OF PHARMACAL RESEARCH,2012,35(12):2147-2151.
APA Liu, Xu.,Zhan, Rui.,Wang, Wei Guang.,Du, Xue.,Li, Yan.,...&Sun, Han Dong.(2012).Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens.ARCHIVES OF PHARMACAL RESEARCH,35(12),2147-2151.
MLA Liu, Xu,et al."Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens".ARCHIVES OF PHARMACAL RESEARCH 35.12(2012):2147-2151.
Files in This Item: Download All
File Name/Size DocType Version Access License
art%3A10.1007%2Fs122(369KB) 开放获取CC BY-NC-NDView Download
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu, Xu]'s Articles
[Zhan, Rui]'s Articles
[Wang, Wei Guang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu, Xu]'s Articles
[Zhan, Rui]'s Articles
[Wang, Wei Guang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu, Xu]'s Articles
[Zhan, Rui]'s Articles
[Wang, Wei Guang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: art%3A10.1007%2Fs12272-012-1212-6.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.