Five new phenolic compounds from Dendrobium aphyllum
Yang, Dan1,2,4; Liu, Liang-Yan3; Cheng, Zhong-Quan4; Xu, Feng-Qing2; Fan, Wei-Wei2; Zi, Cheng-Ting1,2; Dong, Fa-Wu2; Zhou, Jun2; Ding, Zhong-Tao1; Hu, Jiang-Miao2
2015
Source PublicationFITOTERAPIA
Volume100Pages:11-18
AbstractOne new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscopic analyses, and the absolute configuration of compound 1 was determined by single crystal X-ray diffraction and quantum calculations. Compounds 6,8 and 14 inhibited NO production at the concentration of 25 mu M in LPS-stimulated RAW264.7 cells with the inhibition (%) of 32.48, 35.68, and 38.50. Compound 2 possessed significant DPPH radical scavenging activity with scavenging percentage of 87.97% at the concentration of 100 mu g/mL. (C) 2014 Elsevier B.V. All rights reserved.
KeywordDendrobium Aphyllum Phenanthrene Bibenzyl Derivative No Production
DOI10.1016/j.fitote.2014.11.004
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000349881300003
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/20429
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Yunnan Agr Univ, Coll Agron & Biotechnol, Kunming 650201, Peoples R China
4.Guilin Normal Coll, Guilin 541001, Peoples R China
Recommended Citation
GB/T 7714
Yang, Dan,Liu, Liang-Yan,Cheng, Zhong-Quan,et al. Five new phenolic compounds from Dendrobium aphyllum[J]. FITOTERAPIA,2015,100:11-18.
APA Yang, Dan.,Liu, Liang-Yan.,Cheng, Zhong-Quan.,Xu, Feng-Qing.,Fan, Wei-Wei.,...&Hu, Jiang-Miao.(2015).Five new phenolic compounds from Dendrobium aphyllum.FITOTERAPIA,100,11-18.
MLA Yang, Dan,et al."Five new phenolic compounds from Dendrobium aphyllum".FITOTERAPIA 100(2015):11-18.
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