Two new ambuic acid analogs from Pestalotiopsis sp cr013
Xie, Jin1,2; Li, Jing1,2,3; Yang, Yin-He1; Chen, Yu-Hui2; Zhao, Pei-Ji1
2014-12-01
发表期刊PHYTOCHEMISTRY LETTERS
卷号10页码:291-294
摘要Pestalotiopsis is a highly prolific genus with a plethora of diverse secondary metabolites. Pestalotiopsis sp. cr013 was isolated from aeciospores of Cronartium ribicola and subjected to phytochemical investigation based on its special environment. To understand the secondary metabolites of strain Pestalotiopsis sp. cr013, two new compounds 1 and 2 were isolated from solid fermentation products of the fungus. Two new structures were elucidated by extensive spectroscopic analyses, including 1D- and 2D-NMR, and HR-ESI-MS experiments. Compound 1 exhibited weak cytotoxicity activity against five cancer cell lines, with IC50 values of 18.99 mu M (HL-60), 17.68 mu M (SMMC-7721), 18.28 mu M (A-549), 21.67 mu M (MCF-7) and 12.27 mu M (SW480). (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
关键词Pestalotiopsis Sp Cr013 Chemical Constituents Structure Identification Ambuic Acid Analog
DOI10.1016/j.phytol.2014.10.002
收录类别SCI
语种英语
WOS记录号WOS:000347915800076
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/20424
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Southwest Forestry Univ, Life Sci Coll, Kunming 650224, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Xie, Jin,Li, Jing,Yang, Yin-He,et al. Two new ambuic acid analogs from Pestalotiopsis sp cr013[J]. PHYTOCHEMISTRY LETTERS,2014,10:291-294.
APA Xie, Jin,Li, Jing,Yang, Yin-He,Chen, Yu-Hui,&Zhao, Pei-Ji.(2014).Two new ambuic acid analogs from Pestalotiopsis sp cr013.PHYTOCHEMISTRY LETTERS,10,291-294.
MLA Xie, Jin,et al."Two new ambuic acid analogs from Pestalotiopsis sp cr013".PHYTOCHEMISTRY LETTERS 10(2014):291-294.
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