Two new ambuic acid analogs from Pestalotiopsis sp cr013
Xie, Jin1,2; Li, Jing1,2,3; Yang, Yin-He1; Chen, Yu-Hui2; Zhao, Pei-Ji1
2014-12-01
Source PublicationPHYTOCHEMISTRY LETTERS
Volume10Pages:291-294
AbstractPestalotiopsis is a highly prolific genus with a plethora of diverse secondary metabolites. Pestalotiopsis sp. cr013 was isolated from aeciospores of Cronartium ribicola and subjected to phytochemical investigation based on its special environment. To understand the secondary metabolites of strain Pestalotiopsis sp. cr013, two new compounds 1 and 2 were isolated from solid fermentation products of the fungus. Two new structures were elucidated by extensive spectroscopic analyses, including 1D- and 2D-NMR, and HR-ESI-MS experiments. Compound 1 exhibited weak cytotoxicity activity against five cancer cell lines, with IC50 values of 18.99 mu M (HL-60), 17.68 mu M (SMMC-7721), 18.28 mu M (A-549), 21.67 mu M (MCF-7) and 12.27 mu M (SW480). (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
KeywordPestalotiopsis Sp Cr013 Chemical Constituents Structure Identification Ambuic Acid Analog
DOI10.1016/j.phytol.2014.10.002
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Plant Sciences
WOS SubjectBiochemistry & Molecular Biology ; Plant Sciences
WOS IDWOS:000347915800076
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/20424
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Southwest Forestry Univ, Life Sci Coll, Kunming 650224, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Xie, Jin,Li, Jing,Yang, Yin-He,et al. Two new ambuic acid analogs from Pestalotiopsis sp cr013[J]. PHYTOCHEMISTRY LETTERS,2014,10:291-294.
APA Xie, Jin,Li, Jing,Yang, Yin-He,Chen, Yu-Hui,&Zhao, Pei-Ji.(2014).Two new ambuic acid analogs from Pestalotiopsis sp cr013.PHYTOCHEMISTRY LETTERS,10,291-294.
MLA Xie, Jin,et al."Two new ambuic acid analogs from Pestalotiopsis sp cr013".PHYTOCHEMISTRY LETTERS 10(2014):291-294.
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