Enmein-type diterpenoids from the aerial parts of Isodon rubescens and their cytotoxicity
Liu, Xu1; Wang, Wei-Guang2; Du, Xue2; Li, Xiao-Nian2; Kong, Ling-Mei2; Li, Yan2; Pu, Jian-Xin2; Wu, Ji-Zhou1; Sun, Han-Dong2
2012-12-01
Source PublicationFITOTERAPIA
Volume83Issue:8Pages:1451-1455
AbstractThree new enmein-type diterpenoids, jianshirubesins A-C (1-3), together with ten known compounds, were isolated from the aerial parts of Isodon rubescens. Their structures were established by using spectroscopic methods, and the absolute configuration of compound 1 was confirmed by a single-crystal X-ray diffraction analysis. All compounds except 3 were evaluated for their in vitro cytotoxicity by MTT assay, and compounds 5 and 10 exhibited significant inhibitory ability on selected cell lines. (C) 2012 Elsevier B.V. All rights reserved.
KeywordJianshirubesins A-c Enmein-type Diterpenoid Isodon Rubescens Cytotoxic Activity
DOI10.1016/j.fitote.2012.08.009
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000312916400022
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/20392
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Huazhong Univ Sci & Technol, Tongji Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Liu, Xu,Wang, Wei-Guang,Du, Xue,et al. Enmein-type diterpenoids from the aerial parts of Isodon rubescens and their cytotoxicity[J]. FITOTERAPIA,2012,83(8):1451-1455.
APA Liu, Xu.,Wang, Wei-Guang.,Du, Xue.,Li, Xiao-Nian.,Kong, Ling-Mei.,...&Sun, Han-Dong.(2012).Enmein-type diterpenoids from the aerial parts of Isodon rubescens and their cytotoxicity.FITOTERAPIA,83(8),1451-1455.
MLA Liu, Xu,et al."Enmein-type diterpenoids from the aerial parts of Isodon rubescens and their cytotoxicity".FITOTERAPIA 83.8(2012):1451-1455.
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