New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum
Ma, Juan; Zhao, Pei-Ji; Shen, Yue-Mao
2007-06-01
发表期刊ARCHIVES OF PHARMACAL RESEARCH
ISSN0253-6269
卷号30期号:6页码:670-673
摘要By using preparative TLC as the critical isolation procedure, two compounds, including one new amide N-glycosides of ansamitocin (2), were isolated from Actinosynnema pretiosum. The compounds were elucidated as N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-2, named ansamitocinoside P-2 (1), and N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-1, named ansamitocinoside P-1 (2) on the basis of their spectral data. The H-1-NMR and C-13-NMR assignments were made for 1 and 2 while the C-13-NMR assignment for 1 was revised. Bioassay results showed that 1 had antineoplastic activity.
关键词Actinosynnema Pretiosum Ansamitocin Ansamitocinoside Antineoplastic Activity
学科领域Chemistry ; Medicinal ; Pharmacology & Pharmacy
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000248367900002
引用统计
被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/2039
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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Ma, Juan,Zhao, Pei-Ji,Shen, Yue-Mao. New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum[J]. ARCHIVES OF PHARMACAL RESEARCH,2007,30(6):670-673.
APA Ma, Juan,Zhao, Pei-Ji,&Shen, Yue-Mao.(2007).New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum.ARCHIVES OF PHARMACAL RESEARCH,30(6),670-673.
MLA Ma, Juan,et al."New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum".ARCHIVES OF PHARMACAL RESEARCH 30.6(2007):670-673.
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