New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum | |
Ma, Juan; Zhao, Pei-Ji; Shen, Yue-Mao | |
2007-06-01 | |
发表期刊 | ARCHIVES OF PHARMACAL RESEARCH
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ISSN | 0253-6269 |
卷号 | 30期号:6页码:670-673 |
摘要 | By using preparative TLC as the critical isolation procedure, two compounds, including one new amide N-glycosides of ansamitocin (2), were isolated from Actinosynnema pretiosum. The compounds were elucidated as N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-2, named ansamitocinoside P-2 (1), and N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-1, named ansamitocinoside P-1 (2) on the basis of their spectral data. The H-1-NMR and C-13-NMR assignments were made for 1 and 2 while the C-13-NMR assignment for 1 was revised. Bioassay results showed that 1 had antineoplastic activity. |
关键词 | Actinosynnema Pretiosum Ansamitocin Ansamitocinoside Antineoplastic Activity |
学科领域 | Chemistry ; Medicinal ; Pharmacology & Pharmacy |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000248367900002 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/2039 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Ma, Juan,Zhao, Pei-Ji,Shen, Yue-Mao. New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum[J]. ARCHIVES OF PHARMACAL RESEARCH,2007,30(6):670-673. |
APA | Ma, Juan,Zhao, Pei-Ji,&Shen, Yue-Mao.(2007).New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum.ARCHIVES OF PHARMACAL RESEARCH,30(6),670-673. |
MLA | Ma, Juan,et al."New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum".ARCHIVES OF PHARMACAL RESEARCH 30.6(2007):670-673. |
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