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题名: New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum
作者: Ma, Juan; Zhao, Pei-Ji; Shen, Yue-Mao
刊名: ARCHIVES OF PHARMACAL RESEARCH
关键词: Actinosynnema pretiosum ; ansamitocin ; ansamitocinoside ; antineoplastic activity
英文摘要: By using preparative TLC as the critical isolation procedure, two compounds, including one new amide N-glycosides of ansamitocin (2), were isolated from Actinosynnema pretiosum. The compounds were elucidated as N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-2, named ansamitocinoside P-2 (1), and N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-1, named ansamitocinoside P-1 (2) on the basis of their spectral data. The H-1-NMR and C-13-NMR assignments were made for 1 and 2 while the C-13-NMR assignment for 1 was revised. Bioassay results showed that 1 had antineoplastic activity.
出版日期: 2007-06-01
卷号: 30, 期号:6, 页码:670-673
语种: 英语
收录类别: SCI
学科分类: Chemistry; Medicinal; Pharmacology & Pharmacy
ISSN号: 0253-6269
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/2039
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

Recommended Citation:
Ma, J; Zhao, PJ; Shen, YM.New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum,ARCHIVES OF PHARMACAL RESEARCH,2007,30(6):670-673
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