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题名: Synthesis and biological evaluation of lycorine derivatives as dual inhibitors of human acetylcholinesterase and butyrylcholinesterase
作者: Wang YueHu(王跃虎)1; Wan, Qin-Li3; Gu, Cheng-Ding4; null(罗怀容)3; Long, Chun-Lin1, 2
刊名: CHEMISTRY CENTRAL JOURNAL
出版日期: 2012-09-08
卷号: 6
关键词: Amaryllidaceae alkaloids ; Lycorine ; Acetylcholinesterase ; Butyrylcholinesterase
DOI: 10.1186/1752-153X-6-96
文章类型: Article
英文摘要: Background: Alzheimer's disease (AD) is a neurologically degenerative disorder that affects more than 20 million people worldwide. The selective butyrylcholinesterase (BChE) inhibitors and bivalent cholinesterase (ChE) inhibitors represent new treatments for AD.
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: AMARYLLIDACEAE ALKALOIDS ; ALZHEIMERS-DISEASE ; HOSTA-PLANTAGINEA ; PEPTIDE
收录类别: SCI
语种: 英语
WOS记录号: WOS:000312632100001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20074
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China
2.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
4.Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210093, Jiangsu, Peoples R China
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