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题名: Rubesanolides C-E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity
作者: Zou, Juan1, 2; Pan, Lutai1; Li, Qiji1; Pu, Jianxin2; Yao, Ping3; Zhu, Min4; Banas, Jeffrey A.4; Zhang, Hongjie5; null(孙汉董)2
刊名: ORGANIC & BIOMOLECULAR CHEMISTRY
出版日期: 2012
卷号: 10, 期号:26, 页码:5039-5044
DOI: 10.1039/c2ob25192b
文章类型: Article
英文摘要: Phytochemical study of the leaves of the medicinal plant Isodon rubescens led to the isolation of three novel abietane diterpenoids, rubesanolides C-E (1-3). These diterpenes contain a unique.-lactone subgroup formed between C-8 and C-20. Their structures were determined from analysis of spectroscopic data, and were further confirmed by X-ray crystallographic data. The compounds were evaluated for their antibacterial activity, and rubesanolide D (2) demonstrated inhibition activity against biofilm formation of the dental bacterium Streptococcus mutans.
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
收录类别: SCI ; IC
语种: 英语
WOS记录号: WOS:000305191000005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/20066
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Guiyang Coll Tradit Chinese Med, Guiyang 550002, Guizhou, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China
3.Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
4.Univ Iowa, Coll Dent, Dows Inst Dent Res, Iowa City, IA 52242 USA
5.Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
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