Rubesanolides C-E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity
Zou, Juan1,2; Pan, Lutai1; Li, Qiji1; Pu, Jianxin2; Yao, Ping3; Zhu, Min4; Banas, Jeffrey A.4; Zhang, Hongjie5; Sun, Handong2
2012
发表期刊ORGANIC & BIOMOLECULAR CHEMISTRY
卷号10期号:26页码:5039-5044
摘要Phytochemical study of the leaves of the medicinal plant Isodon rubescens led to the isolation of three novel abietane diterpenoids, rubesanolides C-E (1-3). These diterpenes contain a unique.-lactone subgroup formed between C-8 and C-20. Their structures were determined from analysis of spectroscopic data, and were further confirmed by X-ray crystallographic data. The compounds were evaluated for their antibacterial activity, and rubesanolide D (2) demonstrated inhibition activity against biofilm formation of the dental bacterium Streptococcus mutans.
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/20066
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Guiyang Coll Tradit Chinese Med, Guiyang 550002, Guizhou, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunnan, Peoples R China
3.Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
4.Univ Iowa, Coll Dent, Dows Inst Dent Res, Iowa City, IA 52242 USA
5.Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
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Zou, Juan,Pan, Lutai,Li, Qiji,et al. Rubesanolides C-E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2012,10(26):5039-5044.
APA Zou, Juan.,Pan, Lutai.,Li, Qiji.,Pu, Jianxin.,Yao, Ping.,...&Sun, Handong.(2012).Rubesanolides C-E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity.ORGANIC & BIOMOLECULAR CHEMISTRY,10(26),5039-5044.
MLA Zou, Juan,et al."Rubesanolides C-E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity".ORGANIC & BIOMOLECULAR CHEMISTRY 10.26(2012):5039-5044.
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