Chemical constituents of Euphorbia tangutica | |
Zhang, Ben-Yin1,5; Wang, Huan1; Luo, Xiao-Dong2; Du, Zhi-Zhi2; Wu, Hai-Feng3,4; Shen, Jian-Wei1; Zhang, Xiao-feng1 | |
2012 | |
发表期刊 | NATURAL PRODUCT RESEARCH |
卷号 | 26期号:24页码:2309-2315 |
摘要 | Sixteen known compounds isolated from the whole plants of Euphorbia tangutica, including phorbol-13-actate (1) previously synthesised and obtained from a natural source for the first time, were evaluated in vitro against a panel of human cancer cell lines using the MTT method. Among them, ergosterol (6) exhibited significant cytotoxic activity against HL-60 cell line with an IC50 value of 3.3 mu M, and 3 beta,5 alpha-dihydroxy-15 beta-cinnamoyloxy-14-oxolathyra-6Z,12 E-diene (7) also displayed moderate activity. |
关键词 | Euphorbiaceae Euphorbia Tangutica Phorbol-13-actate Ergosterol Cytotoxic Activity |
DOI | 10.1080/14786419.2012.668686 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000310608200004 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/20062 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, NW Inst Plateau Biol, Xining 810008, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China 4.Peking Union Med Coll, Beijing 100193, Peoples R China 5.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Ben-Yin,Wang, Huan,Luo, Xiao-Dong,et al. Chemical constituents of Euphorbia tangutica[J]. NATURAL PRODUCT RESEARCH,2012,26(24):2309-2315. |
APA | Zhang, Ben-Yin.,Wang, Huan.,Luo, Xiao-Dong.,Du, Zhi-Zhi.,Wu, Hai-Feng.,...&Zhang, Xiao-feng.(2012).Chemical constituents of Euphorbia tangutica.NATURAL PRODUCT RESEARCH,26(24),2309-2315. |
MLA | Zhang, Ben-Yin,et al."Chemical constituents of Euphorbia tangutica".NATURAL PRODUCT RESEARCH 26.24(2012):2309-2315. |
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