Chemical constituents of Euphorbia tangutica
Zhang, Ben-Yin1,5; Wang, Huan1; Luo, Xiao-Dong2; Du, Zhi-Zhi2; Wu, Hai-Feng3,4; Shen, Jian-Wei1; Zhang, Xiao-feng1
2012
发表期刊NATURAL PRODUCT RESEARCH
卷号26期号:24页码:2309-2315
摘要Sixteen known compounds isolated from the whole plants of Euphorbia tangutica, including phorbol-13-actate (1) previously synthesised and obtained from a natural source for the first time, were evaluated in vitro against a panel of human cancer cell lines using the MTT method. Among them, ergosterol (6) exhibited significant cytotoxic activity against HL-60 cell line with an IC50 value of 3.3 mu M, and 3 beta,5 alpha-dihydroxy-15 beta-cinnamoyloxy-14-oxolathyra-6Z,12 E-diene (7) also displayed moderate activity.
关键词Euphorbiaceae Euphorbia Tangutica Phorbol-13-actate Ergosterol Cytotoxic Activity
DOI10.1080/14786419.2012.668686
收录类别SCI
语种英语
WOS研究方向Chemistry ; Pharmacology & Pharmacy
WOS类目Chemistry, Applied ; Chemistry, Medicinal
WOS记录号WOS:000310608200004
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/20062
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, NW Inst Plateau Biol, Xining 810008, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
3.Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China
4.Peking Union Med Coll, Beijing 100193, Peoples R China
5.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
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GB/T 7714
Zhang, Ben-Yin,Wang, Huan,Luo, Xiao-Dong,et al. Chemical constituents of Euphorbia tangutica[J]. NATURAL PRODUCT RESEARCH,2012,26(24):2309-2315.
APA Zhang, Ben-Yin.,Wang, Huan.,Luo, Xiao-Dong.,Du, Zhi-Zhi.,Wu, Hai-Feng.,...&Zhang, Xiao-feng.(2012).Chemical constituents of Euphorbia tangutica.NATURAL PRODUCT RESEARCH,26(24),2309-2315.
MLA Zhang, Ben-Yin,et al."Chemical constituents of Euphorbia tangutica".NATURAL PRODUCT RESEARCH 26.24(2012):2309-2315.
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