Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase
Wang, Yue-Hu; Zhang, Zhong-Kai; Yang, Fu-Mei; Sun, Qian-Yun; He, Hong-Ping; Di, Ying-Tong; Mu, Shu-Zhen; Lu, Yang; Chang, Ying; Zheng, Qi-Tai; Ding, Ming; Dong, Jia-Hong; Hao, Xiao-Jiang
2007-09-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号70期号:9页码:1458-1461
摘要Five new benzylphenethylamine alkaloids, hostasine (1), 8-demethoxyhostasine, 8-demethoxy-10-O-methylhostasine, 10-O-methylhostasirie, and 9-O-demethyl-7-O-methyllycorenine, along with 12 known compounds, were isolated from Hosta plantaginea by bioassay-guided fractionation. The structures of the new alkaloids were established by means of extensive spectroscopic methods, and the relative configuration of I was further confirmed by single-crystal X-ray diffraction. 7-Deoxy-trans-dihydronarciclasine (IC50 = 1.80 mu M), a known alkaloid, showed strong activity against tobacco mosaic virus by the half-leaf method. Some of these alkaloids were also evaluated for their inhibitory activity against acetylcholinesterase. 8-Demethoxy-10-O-methylhostasine was found to possess significant activity, with an IC50 of 2.32 mu M.
关键词Amaryllidaceae Alkaloids Cytostatic Activity Steroidal Saponins Hl-60 Cells Hymenocallis Ungeremine Plants Bulbs
学科领域Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np0702077
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000249871200013
引用统计
被引频次:37[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/2005
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Yunnan Acad Agr Sci, Yunnan Key Lab Agr Biotechnol, Kunming 650223, Peoples R China
4.Chinese Acad Sci, Guiyang 550002, Peoples R China
5.Key Lab Chem Nat Prod Guizhou Prov, Guiyang, Peoples R China
6.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
推荐引用方式
GB/T 7714
Wang, Yue-Hu,Zhang, Zhong-Kai,Yang, Fu-Mei,et al. Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase[J]. JOURNAL OF NATURAL PRODUCTS,2007,70(9):1458-1461.
APA Wang, Yue-Hu.,Zhang, Zhong-Kai.,Yang, Fu-Mei.,Sun, Qian-Yun.,He, Hong-Ping.,...&Hao, Xiao-Jiang.(2007).Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase.JOURNAL OF NATURAL PRODUCTS,70(9),1458-1461.
MLA Wang, Yue-Hu,et al."Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase".JOURNAL OF NATURAL PRODUCTS 70.9(2007):1458-1461.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201109230023.pdf(95KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang, Yue-Hu]的文章
[Zhang, Zhong-Kai]的文章
[Yang, Fu-Mei]的文章
百度学术
百度学术中相似的文章
[Wang, Yue-Hu]的文章
[Zhang, Zhong-Kai]的文章
[Yang, Fu-Mei]的文章
必应学术
必应学术中相似的文章
[Wang, Yue-Hu]的文章
[Zhang, Zhong-Kai]的文章
[Yang, Fu-Mei]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。