Four new podocarpane-type trinorditerpenes from Aleurites moluccana

	Four new podocarpane-type trinorditerpenes from Aleurites moluccana
	Liu, Hai-Yang; Li, Shi-Jin ; Zhao, Yi ; Ni, Wei ; Hao, Xiao-Jiang; Li, Jun-Zhu ; Hua, Yan ; Xie, Bai-Bo ; Qing, Chen ; Chen, Chang-Xiang
	2007
发表期刊	HELVETICA CHIMICA ACTA
ISSN	0018-019X
卷号	90 期号:10 页码:2017-2023
摘要	Four new podocarpane-type trinorditerpenenes, (5 beta,10 alpha)-12,13-dihydroxypodocarpa-8,11,13-trien-3-one (1), (5 beta,10 alpha)-12-hydroxy-13-methoxypodocarpa-8,11,13-trien-3-one (2), (5 beta,10 alpha)-13-hydroxy-12-methoxypodocarpa-8,11,13-trien-3-one (3), and (3 alpha,5 beta,10 alpha)-13-methoxypodocarpa-8,11,13-triene-3,12-diol (4), together with four known diterpenes, 12-hydroxy-13-methylpodocarpa-8,11,13-trien-3-one (5), spruceanol (6), ent-3 alpha-hydroxypimara-8(14),15-dien-12-one (7), and ent-3 beta,14 alpha-hydroxypimara-7,9(11),15-triene-12-one (8), were isolated from the twigs and leaves of Aleurites moluccana. Their structures were elucidated by means of comprehensive spectroscopic analyses, including NMR and MS. Except 8, all compounds were evaluated for their cytotoxicity; compound 4 exhibited moderate inhibitory activity against Raji cells with an IC50 value of 4.24 mu g/ml.
关键词	Azadirachta-indica Taiwania-cryptomerioides Stem Bark Tricyclic Diterpenoids Constituents Assay
学科领域	Chemistry ; Multidisciplinary
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000250496100016
引用统计	被引频次：14[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/1971
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Kunming Med Coll, Yunnan Key Lab Pharmacol Nat Prod Res, Kunming 650031, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.SW Forest Coll, Kunming 650224, Peoples R China
推荐引用方式 GB/T 7714	Liu, Hai-Yang,Li, Shi-Jin,Zhao, Yi,et al. Four new podocarpane-type trinorditerpenes from Aleurites moluccana[J]. HELVETICA CHIMICA ACTA,2007,90(10):2017-2023.
APA	Liu, Hai-Yang.,Li, Shi-Jin.,Zhao, Yi.,Ni, Wei.,Hao, Xiao-Jiang.,...&Chen, Chang-Xiang.(2007).Four new podocarpane-type trinorditerpenes from Aleurites moluccana.HELVETICA CHIMICA ACTA,90(10),2017-2023.
MLA	Liu, Hai-Yang,et al."Four new podocarpane-type trinorditerpenes from Aleurites moluccana".HELVETICA CHIMICA ACTA 90.10(2007):2017-2023.

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