Two new alkaloids from Brachystemma calycinum and their inhibitory effects on lymphocyte proliferation

	Two new alkaloids from Brachystemma calycinum and their inhibitory effects on lymphocyte proliferation
	Lu, Qing 1; Zhang, Li 2; He, Guo-Rong 2; Liang, Heng-Xing 1; Du, Guan-Hua 2; Cheng, Yong-Xian 1
	2007
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
卷号	4 期号:12 页码:2948-2952
摘要	Two new alkaloids, brachystemidines F (1) and G (2), were isolated from the roots of Brachystemma calycinum. Their structures were established on the basis of detailed spectroscopic analyses, including extensive NMR and HR-MS techniques. Compound 2, which exhibits an unusual N-hydroxydiazenyl (HO-N=N) moiety, is a potent immunosuppressive agent, as demonstrated by inhibition of mouse T- and B-lymphocyte proliferation, with IC50 values of 6.33 and 5.60 mu g/ml, resp.
学科领域	Biochemistry & Molecular Biology ; Chemistry ; Multidisciplinary
收录类别	SCI
语种	英语
WOS记录号	WOS:000252235500026
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/1953
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Botany, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
推荐引用方式 GB/T 7714	Lu, Qing,Zhang, Li,He, Guo-Rong,et al. Two new alkaloids from Brachystemma calycinum and their inhibitory effects on lymphocyte proliferation[J]. CHEMISTRY & BIODIVERSITY,2007,4(12):2948-2952.
APA	Lu, Qing,Zhang, Li,He, Guo-Rong,Liang, Heng-Xing,Du, Guan-Hua,&Cheng, Yong-Xian.(2007).Two new alkaloids from Brachystemma calycinum and their inhibitory effects on lymphocyte proliferation.CHEMISTRY & BIODIVERSITY,4(12),2948-2952.
MLA	Lu, Qing,et al."Two new alkaloids from Brachystemma calycinum and their inhibitory effects on lymphocyte proliferation".CHEMISTRY & BIODIVERSITY 4.12(2007):2948-2952.

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