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题名: Two new alkaloids from Brachystemma calycinum and their inhibitory effects on lymphocyte proliferation
作者: Lu, Qing1; Zhang, Li2; He, Guo-Rong2; Liang, Heng-Xing1; Du, Guan-Hua2; null(程永现)1
刊名: CHEMISTRY & BIODIVERSITY
英文摘要: Two new alkaloids, brachystemidines F (1) and G (2), were isolated from the roots of Brachystemma calycinum. Their structures were established on the basis of detailed spectroscopic analyses, including extensive NMR and HR-MS techniques. Compound 2, which exhibits an unusual N-hydroxydiazenyl (HO-N=N) moiety, is a potent immunosuppressive agent, as demonstrated by inhibition of mouse T- and B-lymphocyte proliferation, with IC50 values of 6.33 and 5.60 mu g/ml, resp.
出版日期: 2007
卷号: 4, 期号:12, 页码:2948-2952
语种: 英语
ISSN号: 1612-1872
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/1953
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Botany, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

Recommended Citation:
Lu, Q; Zhang, L; He, GR; Liang, HX; Du, GH; Cheng, YX.Two new alkaloids from Brachystemma calycinum and their inhibitory effects on lymphocyte proliferation,CHEMISTRY & BIODIVERSITY,2007,4(12):2948-2952
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