Cytotoxic prenylated bibenzyls and flavonoids from Macaranga kurzii
Yang, Da-Song1,2,3; Wei, Jian-Guo1,2,3; Peng, Wei-Bing4; Wang, Shuang-Mei1,2,3; Sun, Chen4; Yang, Yong-Ping1,2,3; Liu, Ke-Chun4; Li, Xiao-Li1,2,3; Li,XL (reprint author),Chinese Acad Sci,Key Lab Econ Plants & Biotechnol,Kunming 650201,Peoples R China.; li_xiaolill@mail.kib.ac.cn
2014-12-01
发表期刊FITOTERAPIA
卷号99页码:261-266
摘要One unique prenylated bibenzyl, kurzphenol A (1), two new prenylated flavonoids, kurzphenols B and C (2 and 3), as well as fourteen known compounds (4-17) were isolated from the twigs of Macaranga kurzii. Compound 1 was the first example of prenylated bibenzyl which possesses a benzofuran ring. All the known compounds were isolated from M. kurzii for the first time. Their structures were elucidated on the basis of extensive spectroscopic interpretation. Compounds 1-17 were tested for their cytotoxicity against A-549 and Hep G2 cancer cell lines and showed IC50 values in the range of 9.76-30.14 mu g/mL. (C) 2014 Elsevier B.V. All rights reserved.
关键词Macaranga Kurzii Euphorbiaceae Prenylated Flavonoids Prenylated Bibenzyls Cytotoxicity
资助信息National Natural Science Foundation of China [31300293, 81202584]; General Project of Applied Foundation Research, Yunnan Province [2013FB067]; Basic Research Project of Ministry of Science and Technology of China [2012FY110300]; Major State Basic Research Development Program [2010CB951704]
学科领域Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1016/j.fitote.2014.10.003
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000347019000033
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/19378
专题资源植物与生物技术所级重点实验室
通讯作者Li,XL (reprint author),Chinese Acad Sci,Key Lab Econ Plants & Biotechnol,Kunming 650201,Peoples R China.; li_xiaolill@mail.kib.ac.cn
作者单位1.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Germplasm Bank Wild Species Southwest China, Kunming 650201, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Inst Tibetan Plateau Res Kunming, Kunming 650201, Peoples R China
4.Shandong Acad Sci, Inst Biol, Jinan 250014, Peoples R China
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Yang, Da-Song,Wei, Jian-Guo,Peng, Wei-Bing,et al. Cytotoxic prenylated bibenzyls and flavonoids from Macaranga kurzii[J]. FITOTERAPIA,2014,99:261-266.
APA Yang, Da-Song.,Wei, Jian-Guo.,Peng, Wei-Bing.,Wang, Shuang-Mei.,Sun, Chen.,...&li_xiaolill@mail.kib.ac.cn.(2014).Cytotoxic prenylated bibenzyls and flavonoids from Macaranga kurzii.FITOTERAPIA,99,261-266.
MLA Yang, Da-Song,et al."Cytotoxic prenylated bibenzyls and flavonoids from Macaranga kurzii".FITOTERAPIA 99(2014):261-266.
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