Tibetan ethnomedicine is famous worldwide, both for its high effectiveness and unique cultural background. Many poisonous plants have been widely used to treat disorders in the Tibetan medicinal system. In the present review article, some representative poisonous plant species are introduced in terms of their significance in traditional Tibetan medicinal practices. They are Aconitum pendulum, Strychnos nux-vomica, Datura stramonium and Anisodus tanguticus, for which the toxic chemical constituents, bioactivities and pharmacological functions are reviewed herein. The most important toxins include aconitine, strychnine, scopolamine, and anisodamine. These toxic plants are still currently in use for pain-reduction and other purposes by Tibetan healers after processing.
National Natural Science Foundation of China 
; Ministry of Education of China [B08044, MUC985, YLDX01013]
; Beijing and State College Students' Scientific Research and Entrepreneurial Action [BEIJ2013110006, GCCX2014110024]
; Ministry of Science and Technology of China [2012FY110300]