Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum

doi:10.1016/j.tet.2015.03.005

	Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum
	Liu, Hong-Xin 1,2,3,4; Tan, Hai-Bo 3; He, Meng-Ting 5; Li, Ling 5; Wang, Yue-Hu1,2 ; Long, Chun-Lin 1,2,6; Wang,YH (reprint author),Chinese Acad Sci,Key Lab Econ Plants & Biotechnol,Kunming Inst Bot,Kunming 650201,Peoples R China.; wan-gyuehu@mail.kib.ac.cn ; long@mail.kib.ac.cn
	2015-04-22
发表期刊	TETRAHEDRON
卷号	71 期号:16 页码:2369-2375
摘要	Two hydroxychavicol heterodimers comprising phenylpropanoid and monoterpene constituent units, named nudibaccatumins A (1) and B (2), were isolated as an inseparable mixture from the aerial parts of Piper nudibaccatum. Their absolute configurations were confirmed by total synthesis using ortho-alkylation of hydroxychavicol with myrtenyl bromide as the key reaction. The two new compounds (1 and 2) and their synthetic analogues (3-8) were evaluated for XO inhibitory activity. (C) 2015 Elsevier Ltd. All rights reserved.
关键词	Piper Nudibaccatum Ortho-alkylation Nudibaccatumin a Nudibaccatumin b
学科领域	Chemistry, Organic
DOI	10.1016/j.tet.2015.03.005
收录类别	SCI
语种	英语
WOS记录号	WOS:000352668900005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/19370
专题	资源植物与生物技术所级重点实验室
通讯作者	Wang,YH (reprint author),Chinese Acad Sci,Key Lab Econ Plants & Biotechnol,Kunming Inst Bot,Kunming 650201,Peoples R China.; wan-gyuehu@mail.kib.ac.cn; long@mail.kib.ac.cn
作者单位	1.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Yunnan Key Lab Wild Plant Resources, Kunming Inst Bot, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China 4.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 5.Kunming Med Univ, Biomed Engn Res Ctr, Kunming 650500, Peoples R China 6.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
推荐引用方式 GB/T 7714	Liu, Hong-Xin,Tan, Hai-Bo,He, Meng-Ting,et al. Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum[J]. TETRAHEDRON,2015,71(16):2369-2375.
APA	Liu, Hong-Xin.,Tan, Hai-Bo.,He, Meng-Ting.,Li, Ling.,Wang, Yue-Hu.,...&long@mail.kib.ac.cn.(2015).Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum.TETRAHEDRON,71(16),2369-2375.
MLA	Liu, Hong-Xin,et al."Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum".TETRAHEDRON 71.16(2015):2369-2375.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Liu-2015-Isolation a（536KB）			开放获取	CC BY-NC-ND	浏览下载