| Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens | |
Liu, Xia1,2; Yang, Xing-Wei1,2 ; Chen, Chao-Qun1; Wu, Chun-Yan1; Zhang, Jing-Jing1,2; Ma, Jun-Zeng1; Wang, Huan1; Yang, Li-Xin1; Xu, Gang1
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| 2013-09-01 | |
| Source Publication | JOURNAL OF NATURAL PRODUCTS
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| Volume | 76Issue:9Pages:1612-1618 |
| Abstract | Nine new polyprenylated acylphloroglucinol derivatives, hypercohins B-J (1-9), and nine known analogues were isolated from the aerial parts of Hypericum cohaerens. The structures of 1-9 were elucidated based on spectroscopic analysis, and the absolute configuration of 1 was confirmed by X-ray crystallographic analysis. The inhibitory activities of these isolates on acetylcholinesterase and five human tumor cell lines were tested, and hypercohins B D (1-3) exhibited moderate inhibitory activity (IC50 5.8-17.9 mu M) against the tested tumor cell lines. |
| Indexed By | SCI ; IC |
| Language | 英语 |
| WOS ID | WOS:000330331200014 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/19247 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| Recommended Citation GB/T 7714 | Liu, Xia,Yang, Xing-Wei,Chen, Chao-Qun,et al. Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(9):1612-1618. |
| APA | Liu, Xia.,Yang, Xing-Wei.,Chen, Chao-Qun.,Wu, Chun-Yan.,Zhang, Jing-Jing.,...&Xu, Gang.(2013).Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens.JOURNAL OF NATURAL PRODUCTS,76(9),1612-1618. |
| MLA | Liu, Xia,et al."Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens".JOURNAL OF NATURAL PRODUCTS 76.9(2013):1612-1618. |
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| np400287r.pdf（1022KB） | 开放获取 | CC BY-NC-ND | View Download | |||
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