Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus
Zhang, Mao-Juan1,2; Liu, Bing1,6; Liao, Shang-Gao3,4; Xu, You-Kai1; Feng, De-Qiang2; Ji, Kai-Long1,2; Li, Yan5
2013-08-01
发表期刊MOLECULES
卷号18期号:8页码:9727-9734
摘要Two new compounds, the 6-oxo oleanane-type triterpenoid uncarilic acid, and its 5,6-secotriterpenoid derivative, secouncarilic acid, were isolated from the hooks and stems of Uucaria sessilifructus together with seven known ursane-type triterpenoids. Uncarilic acid is the second 6-oxo oleanane-type triterpenoid ever reported, while secouncarilic acid is the first oleanane-type 5,6-secotriterpenoid. A plausible biosynthetic pathway from uncarilic acid to secouncarilic acid was also postulated. The inhibitory activities of all the nine compounds against LPS-induced nitric oxide production in RAW264.7 macrophages were evaluated.
关键词Uncaria Sessilifructus Uncarilic Acid Secouncarilic Acid Triterpenoids
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Organic
WOS记录号WOS:000330304100066
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/19222
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Key Lab Trop Plant Resource Sci, Xishuangbanna Trop Bot Garden, Mengla 666303, Yunnan, Peoples R China
2.Yunnan Univ Tradit Chinese Med, Coll Tradit Chinese Med, Kunming 650200, Yunnan, Peoples R China
3.Guiyang Med Coll, Engn Res Ctr Dev & Applicat Ethn Med, Sch Pharm, Guiyang 550004, Guizhou, Peoples R China
4.Guiyang Med Coll, TCM, Sch Pharm, Guiyang 550004, Guizhou, Peoples R China
5.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
6.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
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Zhang, Mao-Juan,Liu, Bing,Liao, Shang-Gao,et al. Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus[J]. MOLECULES,2013,18(8):9727-9734.
APA Zhang, Mao-Juan.,Liu, Bing.,Liao, Shang-Gao.,Xu, You-Kai.,Feng, De-Qiang.,...&Li, Yan.(2013).Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus.MOLECULES,18(8),9727-9734.
MLA Zhang, Mao-Juan,et al."Uncarilic Acid and Secouncarilic Acid, Two New Triterpenoids from Uucaria sessilifructus".MOLECULES 18.8(2013):9727-9734.
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