Eight new hydroperoxides and a new enone of germacrane-type sesquiterpenoids were isolated from the aerial parts of eight different samples of Eupatorium heterophyllum DC. (Asteraceae) collected in P.R. China. The structures were determined based on spectroscopic analyses. Seven of the eight samples produced hiyodorilactone A as a major constituent, while one afforded neither hiyodorilactone nor hydroperoxide. The results indicated the presence of diversity within this species.
1.Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Forestry & Forest Prod Res Inst, Tsukuba, Ibaraki 3058687, Japan 4.Rikkyo Univ, Dept Chem, Toshima Ku, Tokyo 1718501, Japan
Saito,Yoshinori;Mukai,Tomomi;Iwamoto,Yuko;Baba,Makiko;Takiguchi,Koji;Okamoto,Yasuko;Gong,Xun;Kawahara,Takayuki;Kuroda,Chiaki;Tori,Motoo.Germacranolides and Their Diversity of Eupatorium heterophyllum Collected in PR China,CHEMICAL & PHARMACEUTICAL BULLETIN,2014,183(1):16-26