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题名: Notes on Early Land Plants Today. 62. A synopsis of Myriocoleopsis (Lejeuneaceae, Marchantiophyta) with special reference to transfer of Cololejeunea minutissima to Myriocoleopsis
作者: Yu, Ying1, 2; Pocs, Tamas3; Zhu, Rui-Liang1, 4
刊名: PHYTOTAXA
关键词: MAXIMUM-LIKELIHOOD ; PHOMA ; PROBABILITY ; PHYLOGENY ; INFERENCE ; GENERA ; TREES ; TOOLS ; asexual states ; coelomycetes ; molecular phylogeny ; morphology
英文摘要: During the process exploring anti-viral compounds from Phyllanthus species, eight new highly oxygenated bisabolane sesquiterpenoid glycoside phyllaemblicins G1-G8 (1-8) were isolated from Phyllanthus emblica, along with three known compounds, phyllaemblicin F (9), phyllaemblic acid (10) and glochicoccin D (11). Phyllaemblicin G2 (2), bearing a tricyclo [3.1.1.1] oxygen bridge ring system, is an unusual sesquiterpenoid glycoside, while phyllaemblicins G6-G8 (6-8) are dimeric sesquiterpenoid glycosides with two norbisabolane units connecting through a disaccharide. All the structures were elucidated by the extensive analysis of HRMS and NMR data. The relative configuration of phyllaemblicin G2 was constructed based on heteronuclear coupling constants measurement, and the absolute configurations for all new compounds were established by calculated electronic circular dichroism (ECD) using time dependent density functional theory. The sesquiterpenoid glycoside dimers 6-9 displayed potential anti-hepatitis B virus (HBV) activities, especially for the new compound 6 with IC50 of 8.53 +/- 0.97 and 5.68 +/- 1.75 mu M towards the HBV surface antigen (HBsAg) and HBV excreted antigen (HBeAg) secretion, respectively.
出版日期: 2014-10-24
卷号: 183, 期号:4, 页码:293-297
语种: 英语
收录类别: SCI
学科分类: Plant Sciences
ISSN号: 1179-3155
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/18490
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

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作者单位: 1.E China Normal Univ, Sch Life Sci, Dept Biol, Shanghai 200241, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Biodivers & Biogeog East Asia, Kunming 650201, Peoples R China
3.Eszterhazy Coll, Inst Biol, Dept Bot, H-3301 Eger, Hungary
4.E China Normal Univ, Shanghai Key Lab Urban Ecol Processes & Ecorestor, Shanghai 200241, Peoples R China

Recommended Citation:
Yu,Ying;Pocs,Tamas;Zhu,Rui-Liang.Notes on Early Land Plants Today. 62. A synopsis of Myriocoleopsis (Lejeuneaceae, Marchantiophyta) with special reference to transfer of Cololejeunea minutissima to Myriocoleopsis,PHYTOTAXA,2014,12(43):8764-8774
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