Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.
Four new 5 beta,19-epoxycucurbitacins, kuguacins T-W (1-4, resp.), along with nine known cucurbitane derivatives, 5-13, were obtained from the fresh fruit of Momordica chrantia. Structures of the new metabolites were elucidated as 5 beta,19-epoxy-25-hydroxycucurbitane-3,7,23-trione (1), 5 beta,19-epoxy-3,7-dioxo-23,24,25,26,27-pentanorcucurbitan-22-oic acid (2), 5 beta,19-epoxy-3 beta-hydroxycucurbit-24-ene-7,23-dione (3), and 5 beta, 19-epoxy-25-hydroxycucurbit-23-ene-3,7-dione (4), by extensive spectroscopic investigations, which were confirmed by a single-crystal X-ray diffraction analyses in the case of compound 4.
1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China 3.Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Peoples R China
Chen,Jian-Chao;Yuan,Xiao-Xi;Zhou,Lin;Liu,Jie-Qing;Nian,Yin;Li,Zhong-Rong;Li,Yan;Xie,Ming-Jin;Qiu,Ming-Hua.Four New Cucurbitacins from the Fruit of Momordica charantia,HELVETICA CHIMICA ACTA,2014,92(12):895-900