Zhu,HJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.
Penicilliumine (1), a new structure was isolated from the fermentation Penicillium commune 366606, a marine-derived fungus isolated from the sea water collected at Qingdao, China. HPLC chiral separation of 1 afforded two enantiomers (-)-penicilliumine and (+)-penicilliumine, respectively. The structure of 1 was established by comprehensive spectroscopic data, and single-crystal X-ray diffraction. The absolute configuration of enantiomers was determined by quantum mechanical computation of electronic circular dichroism (ECD). (C) 2014 Elsevier Ltd. All rights reserved.
1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 2.Hebei Univ, Chinese Ctr Chiral, Key Lab Med Chem & Mol Diag, Minist Educ, Baoding 071002, Peoples R China 3.Hebei Univ, Coll Pharm Sci, Baoding 071002, Peoples R China 4.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
He,Jiang-Bo;Ji,Yan-Nan;Hu,Dong-Bao;Zhang,Shen;Yan,Hui;Liu,Xin-Chun;Luo,Huai-Rong;Zhu,Hua-Jie.Structure and absolute configuration of penicilliumine, a new alkaloid from Penicillium commune 366606,TETRAHEDRON LETTERS,2014,114(8):1747-1759