| Talaflavuterpenoid A, a new nardosinane-type sesquiterpene from Talaromyces flavus | |
He, Jun-Wei1; Liang, Hao-Xian1; Gao, Hao1; Kuang, Run-Qiao1; Chen, Guo-Dong1; Hu, Dan1; Wang, Chuan-Xi1; Liu, Xing-Zhong2; Li, Yan3 ; Yao, Xin-Sheng1; Gao,H (reprint author),Jinan Univ,Inst Tradit Chinese Med & Nat Prod,Coll Pharm,Guangzhou 510632,Guangdong,Peoples R China.; tghao@jnu.edu.cn; tyaoxs@jnu.edu.cn
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| 2014 | |
| Source Publication | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| ISSN | 1028-6020 |
| Volume | 16Issue:10Pages:1029-1034 |
| Abstract | Talaflavuterpenoid A (1), a new nardosinane-type sesquiterpene, was isolated from the wetland soil-derived fungus Talaromyces flavus BYD07-13, and its structure was elucidated on the basis of HR-MS, NMR, and X-ray diffraction analysis. The absolute configuration of 1 was established by comparing the experimental electronic circular dichroism (ECD) spectrum with the calculated ECD spectra. Its cytotoxic effects on five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480), and antimicrobial activity against Escherichia coli, Staphylococcus aureus, Candida albicans, and Aspergillus niger were evaluated. This is the first report of the presence of nardosinane-type sesquiterpene in Talaromyces sp. |
| Keyword | Wetland Soil-derived Fungus Talaromyces Flavus Nardosinane-type Sesquiterpene Structure Elucidation Biological Activities |
| Subject Area | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| DOI | 10.1080/10286020.2014.933812 |
| Indexed By | SCI ; IC |
| Language | 英语 |
| WOS ID | WOS:000342303100009 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/18430 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Gao,H (reprint author),Jinan Univ,Inst Tradit Chinese Med & Nat Prod,Coll Pharm,Guangzhou 510632,Guangdong,Peoples R China.; tghao@jnu.edu.cn; tyaoxs@jnu.edu.cn |
| Affiliation | 1.Jinan Univ, Inst Tradit Chinese Med & Nat Prod, Coll Pharm, Guangzhou 510632, Guangdong, Peoples R China 2.Chinese Acad Sci, State Key Lab Mycol, Inst Microbiol, Beijing 100190, Peoples R China 3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West C, Kunming Inst Bot, Kunming 650204, Peoples R China |
| Recommended Citation GB/T 7714 | He, Jun-Wei,Liang, Hao-Xian,Gao, Hao,et al. Talaflavuterpenoid A, a new nardosinane-type sesquiterpene from Talaromyces flavus[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2014,16(10):1029-1034. |
| APA | He, Jun-Wei.,Liang, Hao-Xian.,Gao, Hao.,Kuang, Run-Qiao.,Chen, Guo-Dong.,...&tyaoxs@jnu.edu.cn.(2014).Talaflavuterpenoid A, a new nardosinane-type sesquiterpene from Talaromyces flavus.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,16(10),1029-1034. |
| MLA | He, Jun-Wei,et al."Talaflavuterpenoid A, a new nardosinane-type sesquiterpene from Talaromyces flavus".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 16.10(2014):1029-1034. |
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