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题名: Talaflavuterpenoid A, a new nardosinane-type sesquiterpene from Talaromyces flavus
作者: He, Jun-Wei1; Liang, Hao-Xian1; Gao, Hao1; Kuang, Run-Qiao1; Chen, Guo-Dong1; Hu, Dan1; Wang, Chuan-Xi1; Liu, Xing-Zhong2; null(李艳)3; Yao, Xin-Sheng1
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
关键词: wetland soil-derived fungus ; Talaromyces flavus ; nardosinane-type sesquiterpene ; structure elucidation ; biological activities
英文摘要: Talaflavuterpenoid A (1), a new nardosinane-type sesquiterpene, was isolated from the wetland soil-derived fungus Talaromyces flavus BYD07-13, and its structure was elucidated on the basis of HR-MS, NMR, and X-ray diffraction analysis. The absolute configuration of 1 was established by comparing the experimental electronic circular dichroism (ECD) spectrum with the calculated ECD spectra. Its cytotoxic effects on five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480), and antimicrobial activity against Escherichia coli, Staphylococcus aureus, Candida albicans, and Aspergillus niger were evaluated. This is the first report of the presence of nardosinane-type sesquiterpene in Talaromyces sp.
出版日期: 2014
卷号: 16, 期号:10, 页码:1029-1034
语种: 英语
收录类别: SCI ; IC
学科分类: Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
ISSN号: 1028-6020
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/18430
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Jinan Univ, Inst Tradit Chinese Med & Nat Prod, Coll Pharm, Guangzhou 510632, Guangdong, Peoples R China
2.Chinese Acad Sci, State Key Lab Mycol, Inst Microbiol, Beijing 100190, Peoples R China
3.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West C, Kunming Inst Bot, Kunming 650204, Peoples R China

Recommended Citation:
He,Jun-Wei;Liang,Hao-Xian;Gao,Hao;Kuang,Run-Qiao;Chen,Guo-Dong;Hu,Dan;Wang,Chuan-Xi;Liu,Xing-Zhong;Li,Yan;Yao,Xin-Sheng.Talaflavuterpenoid A, a new nardosinane-type sesquiterpene from Talaromyces flavus,JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2014,16(10):1029-1034
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