Long,CL (reprint author),Minzu Univ China,Coll Life & Environm Sci,Beijing 100081,Peoples R China.
Eight compounds including four caffeoyl phenylpropanoid glycosides, jasnervosides A-D (1-4), one monoterpenoid glycoside, jasnervoside E (5), and three secoiridoid glycosides, jasnervosides F-H (10-12), were isolated from the stems of Jasminum nervosum Lour. (Oleaceae), along with four known compounds, poliumoside (6), verbascoside (7), alpha-L-rhamnopyranosyl-(1 -> 3)-O-(alpha-L-rhamnopyranosyl(1 -> 6)-1-O-E-caffeoyl-beta-D-glucopyranoside (8), and jaspolyanthoside (9). Their structures were elucidated on the basis of their physicochemical and spectroscopic properties. Compounds 1,2,4 and 11 displayed potent antioxidant activities in the DPPH assay, while 2 and 3 displayed good activities against LPS-induced TNF-alpha and IL-1 beta production in BV2 cells. Compounds 1-5 and 10-12 were evaluated for their cytotoxic activities against three human cancer cell lines (A-549, Bel-7402, and HCT-8), but none displayed significant activity. (C) 2014 Elsevier Ltd. All rights reserved.
1.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China 2.CUNY, Lehman Coll, Dept Biol Sci, Bronx, NY 10468 USA 3.CUNY, Grad Ctr, Bronx, NY 10468 USA 4.Chinese Acad Sci, Kunming Inst Bot, Kunming 650201, Peoples R China
Guo,Zhi-yong;Li,Ping;Huang,Wen;Wang,Jian-jun;Liu,Yu-jing;Liu,Bo;Wang,Ye-ling;Wu,Shi-Biao;Kennelly,Edward J.;Long,Chun-lin.Antioxidant and anti-inflammatory caffeoyl phenylpropanoid and secoiridoid glycosides from Jasminum nervosum stems, a Chinese folk medicine,PHYTOCHEMISTRY,2014,106():124-133