Two new polyprenylated benzophenones, hypelodins A (1) and B (2), were isolated from the aerial parts of the Chinese medicinal plant Hyperium elodeoides (Choisy). Their structures were elucidated on the basis of spectroscopic evidence. Hypelodin A (1) is a polyprenylated benzophenone having a tetrahydropyrane ring with three prenyl groups and one 4-methyl-1,3-pentadiene moiety, while hypelodin B (2) has a cage-like structure with a 6/6/5/7/6/5 hexacyclic ring system.
1.Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan 2.Tokushima Univ Hosp, Dept Clin Pharm, Tokushima 7708503, Japan 3.Sojo Univ, Fac Pharmaceut Sci, Kumamoto 8620082, Japan 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
Hashida,Chika;Tanaka,Naonobu;Kawazoe,Kazuyoshi;Murakami,Kotaro;Sun,Han-Dong;Takaishi,Yoshihisa;Kashiwada,Yoshiki.Hypelodins A and B, polyprenylated benzophenones from Hypericum elodeoides,JOURNAL OF NATURAL MEDICINES,2014,68(4):737-742