Two novel diterpenoids, japodagricanones A (1) and B (2), along with their biogenetically related diterpenoid 15-epi-4E-jatrogrossidentadion (3), were isolated from the leaves and twigs of Jatropha podagrica. Japodagricanones A (1) and B (2) are the first C-5-nor lathyrane-type diterpenoids. Their structures were established using spectroscopic data, including MS, NMR and ECD data. A plausible biosynthetic pathway for their generation was also proposed. (C) 2014 Elsevier B.V. All rights reserved.
1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Gansu Agr Univ, Coll Biotechnol, Gansu Key Lab Crop Improvement & Germplasm Enhanc, Lanzhou 730070, Gansu, Peoples R China
Liu,Wei-Wei;Zhang,Yu;Yuan,Chun-Mao;Yu,Chun;Ding,Jia-Ying;Li,Xiao-Xiao;Hao,Xiao-Jiang;Wang,Qing;Li,Shun-Lin.Japodagricanones A and B, novel diterpenoids from Jatropha podagrica,FITOTERAPIA,2014,98():156-159