| New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities | |
Shi, Yiming1,4 ; Zhong, Weimao1,4; Chen, Huan2,3; Wang, Ruirui2,3; Shang, Shanzhai1,4; Liang, Chengqin1,4; Gao, Zhonghua1,4; Zheng, Yongtang2,3; Xiao, Weilie1; Sun, Handong1; Xiao, WL (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China.; xwl@mail.kib.ac.cn; hdsun@mail.kib.ac.cn
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| 2014-08-01 | |
| 发表期刊 | CHINESE JOURNAL OF CHEMISTRY
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| ISSN | 1001-604X |
| 卷号 | 32期号:8页码:734-740 |
| 摘要 | Six new lignans (1-6), as well as five known ones (7-11) were isolated from the leaves and stems of Schisandra chinensis. The structures of 1-6 were established on the basis of spectroscopic methods including 1D-and 2D-NMR techniques and CD experiments. Compound 1 was the first example of naturally occurring N-containing lignans featuring a nicotinoyl group. All the new compounds were evaluated for their anti-HIV-1 activities and showed EC50 values in the range 17.89-138.23 mu g/mL. |
| 关键词 | Schisandraceae Schisandra Chinensis Lignan Anti-hiv-1 |
| 学科领域 | Chemistry, Multidisciplinary |
| DOI | 10.1002/cjoc.201400001 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000341236900015 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/18258 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Xiao, WL (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China.; xwl@mail.kib.ac.cn; hdsun@mail.kib.ac.cn |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shi, Yiming,Zhong, Weimao,Chen, Huan,et al. New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities[J]. CHINESE JOURNAL OF CHEMISTRY,2014,32(8):734-740. |
| APA | Shi, Yiming.,Zhong, Weimao.,Chen, Huan.,Wang, Ruirui.,Shang, Shanzhai.,...&hdsun@mail.kib.ac.cn.(2014).New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities.CHINESE JOURNAL OF CHEMISTRY,32(8),734-740. |
| MLA | Shi, Yiming,et al."New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities".CHINESE JOURNAL OF CHEMISTRY 32.8(2014):734-740. |
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