New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities
Shi, Yiming1,4; Zhong, Weimao1,4; Chen, Huan2,3; Wang, Ruirui2,3; Shang, Shanzhai1,4; Liang, Chengqin1,4; Gao, Zhonghua1,4; Zheng, Yongtang2,3; Xiao, Weilie1; Sun, Handong1; Xiao, WL (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China.; xwl@mail.kib.ac.cn; hdsun@mail.kib.ac.cn
2014-08-01
发表期刊CHINESE JOURNAL OF CHEMISTRY
ISSN1001-604X
卷号32期号:8页码:734-740
产权排序第一
摘要Six new lignans (1-6), as well as five known ones (7-11) were isolated from the leaves and stems of Schisandra chinensis. The structures of 1-6 were established on the basis of spectroscopic methods including 1D-and 2D-NMR techniques and CD experiments. Compound 1 was the first example of naturally occurring N-containing lignans featuring a nicotinoyl group. All the new compounds were evaluated for their anti-HIV-1 activities and showed EC50 values in the range 17.89-138.23 mu g/mL.
关键词Schisandraceae Schisandra Chinensis Lignan Anti-hiv-1
学科领域Chemistry, Multidisciplinary
DOI10.1002/cjoc.201400001
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
WOS记录号WOS:000341236900015
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18258
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Xiao, WL (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China.; xwl@mail.kib.ac.cn; hdsun@mail.kib.ac.cn
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China
3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Shi, Yiming,Zhong, Weimao,Chen, Huan,et al. New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities[J]. CHINESE JOURNAL OF CHEMISTRY,2014,32(8):734-740.
APA Shi, Yiming.,Zhong, Weimao.,Chen, Huan.,Wang, Ruirui.,Shang, Shanzhai.,...&hdsun@mail.kib.ac.cn.(2014).New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities.CHINESE JOURNAL OF CHEMISTRY,32(8),734-740.
MLA Shi, Yiming,et al."New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities".CHINESE JOURNAL OF CHEMISTRY 32.8(2014):734-740.
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