Prenylated chalcones from Desmodium renifolium
Li, Yan-Ping1; Yang, Yu-Chun2; Li, Yin-Ke2; Jiang, Zhi-Yong2; Huang, Xiang-Zhong2; Wang, Wei-Guang3; Gao, Xue-Mei2; Hu, Qiu-Fen2; Gao, XM (reprint author), Yunnan Univ Nationalities, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Yunnan, Peoples R China.; gaoxuemei@hotmail.com; huqiufena@aliyun.com
2014-09-01
发表期刊PHYTOCHEMISTRY LETTERS
ISSN1874-3900
卷号9页码:41-45
产权排序第三
摘要Three new prenylated chalcones, renifolins A-C (1-3), together with seven known ones (4-10), were isolated from whole Desmodium renifolium plants. All of their structures were determined by spectroscopic methods including 1D and 2D NMR. Compounds 1 and 2 are the first naturally occurring chalcones possessing a 4-methylfuran-2(5H)-one unit. All of the isolates were evaluated for cytotoxicity using five tumor cell lines. Compounds 3-8, and 10 exhibited moderate cytotoxicity against certain cell lines with IC50 values from 4.2 to 8.8 mu M. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
关键词Desmodium Renifolium Prenylated Flavonoid Prenylated Chalcone Cytotoxicity
资助信息National Natural Science Foundation of China [21302164]; Excellent Scientific and Technological Team of Yunnan High School [2010CI08]; Yunnan University of Nationalities Green Chemistry and Functional Materials Research for Provincial Innovation Team [2011HC008]; Open Research Fund Program of the Key Laboratory of Ethnic Medicine Resource Chemistry (Yunnan University of Nationalities) [2010XY08]
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytol.2014.04.003
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000340884100009
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18254
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Gao, XM (reprint author), Yunnan Univ Nationalities, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Yunnan, Peoples R China.; gaoxuemei@hotmail.com; huqiufena@aliyun.com
作者单位1.Yunnan Univ Tradit Chinese Med, Sch Pharm, Kunming 650500, Yunnan, Peoples R China
2.Yunnan Univ Nationalities, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Yunnan, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China
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GB/T 7714
Li, Yan-Ping,Yang, Yu-Chun,Li, Yin-Ke,et al. Prenylated chalcones from Desmodium renifolium[J]. PHYTOCHEMISTRY LETTERS,2014,9:41-45.
APA Li, Yan-Ping.,Yang, Yu-Chun.,Li, Yin-Ke.,Jiang, Zhi-Yong.,Huang, Xiang-Zhong.,...&huqiufena@aliyun.com.(2014).Prenylated chalcones from Desmodium renifolium.PHYTOCHEMISTRY LETTERS,9,41-45.
MLA Li, Yan-Ping,et al."Prenylated chalcones from Desmodium renifolium".PHYTOCHEMISTRY LETTERS 9(2014):41-45.
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