Diarylheptanoids and phenylphenalenones from Musa itinerans fruits
Liu, Fang1; Zhang, Yu1; Sun, Qian-Yun2; Yang, Fu-Mei2; Gu, Wei1; Yang, Jun1; Niu, Hong-Mei1; Wang, Yue-Hu1; Long, Chun-Lin1,3,4; Wang,YH (reprint author),Chinese Acad Sci,Kunming Inst Bot,Kunming 650201,Peoples R China.; wangyuehu@mail.kib.ac.cn; long@mail.kib.ac.cn
2014-07-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号103页码:171-177
摘要Two diarylheptanoids, musaitinerins A and B, one heterodimeric phenylphenalenone musaitinerone and four known phenylphenalenones, identified as 4-hydroxy-2-methoxy-9-phenyl-1H-phenalen-1-one, musanolone E, hydroxyanigorufone and irenolone were isolated from the fruits of Musa itinerans Cheesm. Their structures were elucidated using spectroscopic analyses. The antimicrobial activity of these compounds was evaluated against Escherichia coli, Staphylococcus aureus and Candida albicans; the cytotoxic activity of these compounds was also evaluated against human erythromyeloblastoid leukemia (K562) and human alveolar carcinoma epithelial (A549) cell lines, respectively. Musaitinerone and musanolone E exhibited weak effects against the A549 cell line, as compared with adriamycin. However, these two compounds did not exhibit any growth inhibition against 1(562 cells, S. aureus, E. coli or C. albicans. The other compounds were inactive against all of the tested cell lines and microorganisms, even at concentrations as high as 50 mu M. (c) 2014 Elsevier Ltd. All rights reserved.
关键词Musaceae Musa Itinerans Diarylheptanoids Phenylphenalenones Cytotoxicity
资助信息National Natural Science Foundation of China [31070288, 20972166, 31161140345];Natural Science Foundation of Yunnan Province, China [2011FZ205];Ministry of Education of China through its 111 and 985 projects [B08044, MUC98506-01000101, MUC985-9];Japan Society for the Promotion of Science [JSPS/AP/109080]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18213
专题资源植物与生物技术所级重点实验室
通讯作者Wang,YH (reprint author),Chinese Acad Sci,Kunming Inst Bot,Kunming 650201,Peoples R China.; wangyuehu@mail.kib.ac.cn; long@mail.kib.ac.cn
作者单位1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650201, Peoples R China
2.Guizhou Prov & Chinese Acad Sci, Key Lab Chem Nat Prod, Guiyang 550002, Peoples R China
3.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
4.Yunnan Agr Univ, Kunming 650201, Peoples R China
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GB/T 7714
Liu, Fang,Zhang, Yu,Sun, Qian-Yun,et al. Diarylheptanoids and phenylphenalenones from Musa itinerans fruits[J]. PHYTOCHEMISTRY,2014,103:171-177.
APA Liu, Fang.,Zhang, Yu.,Sun, Qian-Yun.,Yang, Fu-Mei.,Gu, Wei.,...&long@mail.kib.ac.cn.(2014).Diarylheptanoids and phenylphenalenones from Musa itinerans fruits.PHYTOCHEMISTRY,103,171-177.
MLA Liu, Fang,et al."Diarylheptanoids and phenylphenalenones from Musa itinerans fruits".PHYTOCHEMISTRY 103(2014):171-177.
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