Cucurbitane-type triterpenoids from the stems and leaves of Momordica charantia
Zhao, Gao-Ting1; Liu, Jie-Qing2; Deng, Yuan-Yuan2,3; Li, Hai-Zhou1; Chen, Jian-Chao2; Zhang, Zhi-Run2; Zhou, Lin2; Qiu, Ming-Hua2,3; Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.; mhchiu@mail.kib.ac.cn
2014-06-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号95页码:75-82
摘要Six new cucurbitane-type triterpenoids, karavilagenin F (1), karavilosides XII and XIII (2, 3), momordicines VI, VII, and VIII (4, 5 and 6), along with four known ones, 5 beta,19-epoxy-25-methoxycucurbita-6,23-diene-3 beta,19-diol (7), 5 beta,19-epoxycucurbita-6, 23-diene-3 beta,19,25-triol (8), kuguacin R (9), and (19R,23E)-5 beta,19-epoxy-19-methoxycucurbita-6,23,25-trien-3 beta-ol (10), were isolated from the stems and leaves of Momordica charantia L. Their chemical structures were elucidated by extensive 1D NMR and 2D NMR (HSQC, HMBC, COSY, and ROESY), MS experiments, and CD spectrum. Compound 6 showed weak cytotoxicity against five human cancer cells lines with IC50 values of 143-20.5 mol/L. (C) 2014 Elsevier B.V. All rights reserved.
关键词Momordica Charantia Cucurbitaceae Cucurbitane-type Triterpenoids Cytotoxicity
资助信息General Program of Natural Science Foundation of China (NSFC) [81373288];Cooperation Program between Guangdong and CAS [1312224900009[2013], 20098091300135];Knowledge Innovation Program of the CAS [KSZD-EW-Z-004-01];Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China [P2010-ZZ14]
学科领域Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1016/j.fitote.2014.03.005
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000336819400010
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18202
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.; mhchiu@mail.kib.ac.cn
作者单位1.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming 650500, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Gao-Ting,Liu, Jie-Qing,Deng, Yuan-Yuan,et al. Cucurbitane-type triterpenoids from the stems and leaves of Momordica charantia[J]. FITOTERAPIA,2014,95:75-82.
APA Zhao, Gao-Ting.,Liu, Jie-Qing.,Deng, Yuan-Yuan.,Li, Hai-Zhou.,Chen, Jian-Chao.,...&mhchiu@mail.kib.ac.cn.(2014).Cucurbitane-type triterpenoids from the stems and leaves of Momordica charantia.FITOTERAPIA,95,75-82.
MLA Zhao, Gao-Ting,et al."Cucurbitane-type triterpenoids from the stems and leaves of Momordica charantia".FITOTERAPIA 95(2014):75-82.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Zhao-2014-Cucurbitan(377KB) 开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhao, Gao-Ting]的文章
[Liu, Jie-Qing]的文章
[Deng, Yuan-Yuan]的文章
百度学术
百度学术中相似的文章
[Zhao, Gao-Ting]的文章
[Liu, Jie-Qing]的文章
[Deng, Yuan-Yuan]的文章
必应学术
必应学术中相似的文章
[Zhao, Gao-Ting]的文章
[Liu, Jie-Qing]的文章
[Deng, Yuan-Yuan]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。