Flavonoids and stilbenoids from Derris eriocarpa
Zhang, Hong-Xia1; Lunga, Paul-Keilah1,2; Li, Zhi-Jian1,3; Dai, Qin1; Du, Zhi-Zhi1; Du,ZZ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.; duzhizhi@mail.kib.ac.cn
2014-06-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号95页码:147-153
摘要One new resveratrol analogue, 1-(3',4',5'-trimethoxyphenyl)-2-methoxy-2-(4 ''-methoxyphenyl)-ethane-1-ol (1), and two new prenylisoflavones, 4'-hydroxy-5,7-dimethoxy-6-(3-methyl-2-butenyl)-isoflavone (2), and derrubon 5-methyl ether (3), together with 17 known compounds including one new natural product, 5,7-dihydroxy-3-[4'-O-(3-methyl-2-butenyl)-Phenyl]-isoflavone (4), were isolated from the stems of ethnomedicinal plant Derris eriocarpa How. (Leguminosae). Their structures were elucidated based on chemical evidence and spectroscopic techniques including two-dimensional NMR methods. All compounds are reported from this species for the first time. Antimicrobial activities of the new compounds were evaluated. Compound 2 exhibited good inhibitory activities against Candida guilliermondii C albicans and Microsporium gypseum with the minimal inhibitory concentration (MIC) values of 12.5 mu g/ml. (C) 2014 Elsevier B.V. All rights reserved.
关键词Derris Eriocarpa Prenylisoflavone Resveratrol Analogue Antimicrobial Activity
资助信息Natural Science Foundation of the Yunnan Province [2013FB065];45th Scientific Research Foundation for the Returned Overseas Chinese Scholars from State Education Ministry;National Science and Technology Support Program of China [2013BAI11B02]
学科领域Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1016/j.fitote.2014.03.015
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000336819400020
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18201
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Du,ZZ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.; duzhizhi@mail.kib.ac.cn
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Univ Yaounde I, Fac Sci, Dept Biochem, Lab Phytobiochem & Med Plants Study, Yaounde, Cameroon
3.Yunnan Univ, Sch Life Sci, Kunming 650091, Peoples R China
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Zhang, Hong-Xia,Lunga, Paul-Keilah,Li, Zhi-Jian,et al. Flavonoids and stilbenoids from Derris eriocarpa[J]. FITOTERAPIA,2014,95:147-153.
APA Zhang, Hong-Xia.,Lunga, Paul-Keilah.,Li, Zhi-Jian.,Dai, Qin.,Du, Zhi-Zhi.,...&duzhizhi@mail.kib.ac.cn.(2014).Flavonoids and stilbenoids from Derris eriocarpa.FITOTERAPIA,95,147-153.
MLA Zhang, Hong-Xia,et al."Flavonoids and stilbenoids from Derris eriocarpa".FITOTERAPIA 95(2014):147-153.
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