中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Chemical and Toxicological Investigations of a Previously Unknown Poisonous European Mushroom Tricholoma terreum
作者: Yin, Xia1, 2; Feng, Tao1; Shang, Jian-Hua1; Zhao, Yun-Li1; Wang, Fang1; Li, Zheng-Hui1; Dong, Ze-Jun1; null(罗晓东)1; Liu, Ji-Kai1
刊名: CHEMISTRY-A EUROPEAN JOURNAL
关键词: enzymes ; natural products ; NMR spectroscopy ; structure elucidation ; X-ray diffraction
英文摘要: The established tradition of consuming and marketing wild mushrooms has focused attention on mycotoxicity, which has become a global issue. In the present study, we describe the toxins found in a previously unknown poisonous European mushroom Tricholoma terreum. Fifteen new triterpenoids terreolidesA-F (1-6) and saponaceolidesH-P (8-16) were isolated from the fruiting bodies of the toxic mushroom T. terreum. TerreolidesA-C (1-3) possessed a unique 5/6/7 trioxaspiroketal system, whereas terreolides D-F (4-6) possessed an unprecedented carbon skeleton. Two abundant compounds in the mushroom, saponaceolideB (7) and saponaceolideM (13), displayed acute toxicity, with LD50 values of 88.3 and 63.7mgkg-1 when administered orally in mice. Both compounds were found to increase serum creatine kinase levels in mice, indicating that T. terreum may be the cause of mushroom poisoning ultimately leading to rhabdomyolysis.
出版日期: 2014-06-02
卷号: 20, 期号:23, 页码:7001-7009
语种: 英语
收录类别: SCI ; IC
ISSN号: 0947-6539
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/18199
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Yin-2014-Chemical and Toxicol.pdf(936KB)----开放获取View Download

作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China

Recommended Citation:
Yin,Xia;Feng,Tao;Shang,Jian-Hua;Zhao,Yun-Li;Wang,Fang;Li,Zheng-Hui;Dong,Ze-Jun;Luo,Xiao-Dong;Liu,Ji-Kai.Chemical and Toxicological Investigations of a Previously Unknown Poisonous European Mushroom Tricholoma terreum,CHEMISTRY-A EUROPEAN JOURNAL,2014,20(23):7001-7009
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yin, Xia]'s Articles
[Feng, Tao]'s Articles
[Shang, Jian-Hua]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yin, Xia]‘s Articles
[Feng, Tao]‘s Articles
[Shang, Jian-Hua]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Yin-2014-Chemical and Toxicol.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace