Five unusual new prenylated chalcones, renifolins D-H (1-5), were isolated from whole Desmodium renifolium plants. All of their structures were determined by spectroscopic methods including 1D and 2D NMR. All of the isolates were evaluated for cytotoxicity using five tumor cell lines. Compounds 2 and 3 exhibited cytotoxicity against A549 cells, with IC50 values of 2.8 and 22 mu M, respectively. (C) 2014 Elsevier B.V. All rights reserved.
1.Yunnan Univ Tradit Chinese Med, Sch Pharm, Kunming 650500, Yunnan, Peoples R China 2.Yunnan Univ Nationalities, State Ethn Affairs Commiss, Key Lab Chem Ethn Med Resources, Kunming 650031, Yunnan, Peoples R China 3.Yunnan Univ Nationalities, Minist Educ, Kunming 650031, Yunnan, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China
Recommended Citation:
Li,Yan-Ping;Yang,Yu-Chun;Li,Yin-Ke;Jiang,Zhi-Yong;Huang,Xiang-Zhong;Wang,Wei-Guang;Gao,Xue-Mei;Hu,Qiu-Fen.Five new prenylated chalcones from Desmodium renifolium,FITOTERAPIA,2014,95():214-219
