| New polyesters from Talaromyces flavus | |
He, Jun-Wei1; Mu, Zhen-Qiang1; Gao, Hao1; Chen, Guo-Dong1; Zhao, Qin1; Hu, Dan1; Sun, Jing-Zu3; Li, Xiao-Xia1; Li, Yan2 ; Liu, Xing-Zhong3; Yao, Xin-Sheng1; Gao,H (reprint author),Jinan Univ,Coll Pharm,Inst Tradit Chinese Med & Nat Prod,Guangzhou 510632,Guangdong,Peoples R China.; tghao@jnu.edu.cn; tyaoxs@jnu.edu.cn
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| 2014-07-22 | |
| 发表期刊 | TETRAHEDRON
 |
| ISSN | 0040-4020 |
| 卷号 | 70期号:29页码:4425-4430 |
| 摘要 | Six new polyesters, talapolyesters A-F (1-4, 14, and 16), together with 11 known ones 15G256 nu (5), 15G256 nu-me (6), 15G256 pi (7), 15G256 beta-2 (8), 15G256 alpha-2 (9), 15G256 alpha-2-me (10), 15G256 iota. (11), 15G256 beta (12), 15G256 alpha (13), 15G256 alpha-1 (15), and 15G256 omega (17), were isolated from the wetland soil-derived fungus Talaromyces flavus BYD07-13, and their structures were determined by NMR and MS spectroscopic data. Among them, 1-4 and 16 were assembled in a different manner from that of the known 256 polyesters. All the polyesters are composed of (R)-2,4-dihydroxy-6-(2-hydroxypropyl)benzoic acid and (R)-3-hydroxybutyric acid/(S)-3,4-dihydroxybutyric acid residues. The absolute configurations of the residues were determined by alkaline hydrolysis. The cytotoxicity against five tumor cell lines of these compounds was examined, and a tight structure-activity relationship is proposed. (C) 2014 Elsevier Ltd. All rights reserved. |
| 关键词 | Talaromyces Flavus Talapolyesters A-f 15g256 Polyesters Wetland Soil-derived Fungus Cytotoxicity |
| 学科领域 | Chemistry, Organic |
| DOI | 10.1016/j.tet.2014.02.060 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000337868400019 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/18185 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Gao,H (reprint author),Jinan Univ,Coll Pharm,Inst Tradit Chinese Med & Nat Prod,Guangzhou 510632,Guangdong,Peoples R China.; tghao@jnu.edu.cn; tyaoxs@jnu.edu.cn |
| 作者单位 | 1.Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Jun-Wei,Mu, Zhen-Qiang,Gao, Hao,et al. New polyesters from Talaromyces flavus[J]. TETRAHEDRON,2014,70(29):4425-4430. |
| APA | He, Jun-Wei.,Mu, Zhen-Qiang.,Gao, Hao.,Chen, Guo-Dong.,Zhao, Qin.,...&tyaoxs@jnu.edu.cn.(2014).New polyesters from Talaromyces flavus.TETRAHEDRON,70(29),4425-4430. |
| MLA | He, Jun-Wei,et al."New polyesters from Talaromyces flavus".TETRAHEDRON 70.29(2014):4425-4430. |
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