One-Step Semisynthesis Method of Spirocurcasone and Pyracurcasone from Curcusones A and B

doi:10.1021/ol500692j

	One-Step Semisynthesis Method of Spirocurcasone and Pyracurcasone from Curcusones A and B
	Li, Xu-Yang 1,2; Yang, Yuan-Feng 1,2; Peng, Xing-Rong 1,2; Li, Ming-Ming 1; Li, Liang-Qun 1,2; Deng, Xu 1; Qin, Hong-Bo 1,2; Liu, Jie-Qing 1; Qiu, Ming-Hua 1,2
	2014-04-18
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	16 期号:8 页码:2196-2199
摘要	High contents of curcusones A and B and trace amounts of spirocurcasone exist in the roots of Jatropha curcas. Here, a one-step semisynthesis method of spirocurcasone and pyracurcasone was built, not only resulted an increased yield of spirocurcasone but also produced pyracurcasone, which exhibited greater cytotoxicity compared to curcusones A and B. The plausible mechanism of the formation of pyracurcasone was proposed, and the proposed biogenetic origin for spirocurcasone by Taglialatela-Scafati was confirmed.
关键词	Jatropha-curcas Diterpenes Dumsin System
资助信息	NSFC [81202437]; NSFY [U1132604]; MOST [2007BAD32B03]; Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China [P2010-ZZ14]
学科领域	Chemistry
DOI	10.1021/ol500692j
收录类别	SCI ; IC ; CCR
语种	英语
WOS研究方向	Chemistry
WOS类目	Chemistry, Organic
WOS记录号	WOS:000334823600032
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/18126
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Photochem & Plant Resources West, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Li, Xu-Yang,Yang, Yuan-Feng,Peng, Xing-Rong,et al. One-Step Semisynthesis Method of Spirocurcasone and Pyracurcasone from Curcusones A and B[J]. ORGANIC LETTERS,2014,16(8):2196-2199.
APA	Li, Xu-Yang.,Yang, Yuan-Feng.,Peng, Xing-Rong.,Li, Ming-Ming.,Li, Liang-Qun.,...&Qiu, Ming-Hua.(2014).One-Step Semisynthesis Method of Spirocurcasone and Pyracurcasone from Curcusones A and B.ORGANIC LETTERS,16(8),2196-2199.
MLA	Li, Xu-Yang,et al."One-Step Semisynthesis Method of Spirocurcasone and Pyracurcasone from Curcusones A and B".ORGANIC LETTERS 16.8(2014):2196-2199.

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