Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii
Xu, Jian1,2; Zeng, Guang-Zhi1; Liu, Yi-Mei2; Chen, Ke-Li2; Sun, Zhang-Hua1,2; Zhang, Yu-Mei1,3; Tan, Ning-Hua1
2014-03-01
发表期刊ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
ISSN0932-0776
卷号69期号:3页码:362-368
摘要Four new sesquiterpenoids, 1 alpha-hydroxymethyl-3 beta-hydroxy-7,8-dihydro-ionol (1), 1 alpha-hydroxymethyl-3 beta-hydroxy-7,8-dihydro-ionol-9-O-beta-D-glucopyranoside (2), (1 alpha,5 beta,7 beta)-3,10(14)-guaiadien-11,12-diol (3), and (6S)-13-O-beta-D-glucopyranosyl-abscisic acid (4), together with 10 known sesquiterpenoids and 5 diterpenes were isolated from the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii. Their structures were mainly determined on the basis of MS, IR, 1D and 2D NMR spectral evidence. Compound 13-epi-toruolsol (17) showed cytotoxicities against BGC-823 and Hela cancer cell lines with IC50 values of 23.0 and 49.9 mu M, and compound 3-epi-triptobenzene B (19) showed cytotoxicities against BGC-823, Hela and A549 cancer cell lines with IC50 values of 19.1, 30.3 and 24.5 mu M, respectively.
关键词Chamaecyparis Obtusa Var. Breviramea F. Crippsii Sesquiterpenoids Diterpenes Cytotoxicity
资助信息The National Natural Science Foundation of China [20972168, 30725048]; National New Drug Innovation Great Project of China [2011ZX09307-002-02]; Natural Science Foundation of Yunnan Province [2010CI048, 2012GA003]
学科领域Chemistry
DOI10.5560/ZNB.2014-3243
收录类别SCI ; IC
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Inorganic & Nuclear ; Chemistry, Organic
WOS记录号WOS:000335614300011
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/18116
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Hubei Univ Chinese Med, Wuhan 430065, Peoples R China
3.Chinese Acad Sci, Xishuangbanna Trop Bot Garden, Key Lab Trop Plant Resource & Sustainable Use, Kunming 650223, Peoples R China
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Xu, Jian,Zeng, Guang-Zhi,Liu, Yi-Mei,et al. Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii[J]. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,2014,69(3):362-368.
APA Xu, Jian.,Zeng, Guang-Zhi.,Liu, Yi-Mei.,Chen, Ke-Li.,Sun, Zhang-Hua.,...&Tan, Ning-Hua.(2014).Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii.ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,69(3),362-368.
MLA Xu, Jian,et al."Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii".ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 69.3(2014):362-368.
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