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题名: Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii
作者: Xu, Jian1, 2; Zeng, Guang-Zhi1; Liu, Yi-Mei2; Chen, Ke-Li2; Sun, Zhang-Hua1, 2; Zhang, Yu-Mei1, 3; Tan, Ning-Hua1
刊名: ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
关键词: Chamaecyparis obtusa var. breviramea f. crippsii ; Sesquiterpenoids ; Diterpenes ; Cytotoxicity
英文摘要: Four new sesquiterpenoids, 1 alpha-hydroxymethyl-3 beta-hydroxy-7,8-dihydro-ionol (1), 1 alpha-hydroxymethyl-3 beta-hydroxy-7,8-dihydro-ionol-9-O-beta-D-glucopyranoside (2), (1 alpha,5 beta,7 beta)-3,10(14)-guaiadien-11,12-diol (3), and (6S)-13-O-beta-D-glucopyranosyl-abscisic acid (4), together with 10 known sesquiterpenoids and 5 diterpenes were isolated from the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii. Their structures were mainly determined on the basis of MS, IR, 1D and 2D NMR spectral evidence. Compound 13-epi-toruolsol (17) showed cytotoxicities against BGC-823 and Hela cancer cell lines with IC50 values of 23.0 and 49.9 mu M, and compound 3-epi-triptobenzene B (19) showed cytotoxicities against BGC-823, Hela and A549 cancer cell lines with IC50 values of 19.1, 30.3 and 24.5 mu M, respectively.
出版日期: 2014-03-01
卷号: 69, 期号:3, 页码:362-368
语种: 英语
收录类别: SCI ; IC
学科分类: Chemistry
ISSN号: 0932-0776
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/18116
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Hubei Univ Chinese Med, Wuhan 430065, Peoples R China
3.Chinese Acad Sci, Xishuangbanna Trop Bot Garden, Key Lab Trop Plant Resource & Sustainable Use, Kunming 650223, Peoples R China

Recommended Citation:
Xu,Jian;Zeng,Guang-Zhi;Liu,Yi-Mei;Chen,Ke-Li;Sun,Zhang-Hua;Zhang,Yu-Mei;Tan,Ning-Hua.Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii,ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,2014,69(3):362-368
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文件名: Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii.pdf
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