中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Mechanisms of Peptide Hormone Secretion
作者: Darren J Michael ; Haijiang Cai ; null(熊文勇) ; Justin Ouyang ; Robert H Chow
刊名: Trends in Endocrinology and Metabolism
英文摘要: According to the classical view, peptide hormones are stored in large dense-core vesicles that release all of their cargo rapidly and completely when they fuse with and flatten into the plasma membrane. However, recent imaging studies suggest that this view is too simple. Even after vesicles fuse with the plasma membrane, cells might control the rate of dispersal of vesicle cargo – either by modulating the properties of the fusion pore that connects the vesicle lumen to the extracellular solution or by storing cargo in states that disperse slowly in the extracellular space. Understanding these mechanisms is important, owing to the increasing prevalence of diseases, such as type 2 diabetes mellitus, which arise from insufficient secretion of peptide hormones.
出版日期: 2006
卷号: 17, 期号:10, 页码:408-415
收录类别: SCI
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/17708
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2006 Mechanisms of Peptide Hormone Secretion.pdf(662KB)----开放获取View Download

Recommended Citation:
Darren J Michael. Mechanisms of Peptide Hormone Secretion[J]. Trends in Endocrinology and Metabolism,2006,17(10):408-415.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Darren J Michael]'s Articles
[Haijiang Cai]'s Articles
[Wenyong Xiong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Darren J Michael]‘s Articles
[Haijiang Cai]‘s Articles
[Wenyong Xiong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2006 Mechanisms of Peptide Hormone Secretion.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace