Cycloartane Triterpenoids from Cassia occidentalis
Shi-Fei Li; Ying-Tong Di; Rong-Tang Zheng; Yue-Hu Wang; Xin Fang; Yu-Zhang; Ling Li; Hong-Ping He; Shun-Lin Li; Xiao-Jiang Hao
Corresponding AuthorHao, XJ (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Heilongtan 650204, Kunming, Peoples R China,
Source PublicationPLANTA MEDICA

A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds were elucidated through detailed spectroscopic analyses, including 1D and 2D NMR techniques, and chemical methods. Compounds 2 and 5 showed modest anti-HIV-1 activities with EC50 values of 2.23 mu M and 4.36 mu M, respectively, in comparison to the positive control.

KeywordCassia Occidentalis Leguminosae Cycloartane Triterpenoids Cycloccidentalic Acids a And b Cycloccidentalisides I-v
Subject AreaPlant Sciences ; Pharmacology & Pharmacy
Indexed BySCI
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000304449300013
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
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GB/T 7714
Shi-Fei Li,Ying-Tong Di,Rong-Tang Zheng,et al. Cycloartane Triterpenoids from Cassia occidentalis[J]. PLANTA MEDICA,2012,78(8):821-827.
APA Shi-Fei Li.,Ying-Tong Di.,Rong-Tang Zheng.,Yue-Hu Wang.,Xin Fang.,...&Xiao-Jiang Hao.(2012).Cycloartane Triterpenoids from Cassia occidentalis.PLANTA MEDICA,78(8),821-827.
MLA Shi-Fei Li,et al."Cycloartane Triterpenoids from Cassia occidentalis".PLANTA MEDICA 78.8(2012):821-827.
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