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题名: Cycloartane Triterpenoids from Cassia occidentalis
作者: Shi-Fei Li; Ying-Tong Di; Rong-Tang Zheng; Yue-Hu Wang; Xin Fang; Yu-Zhang; Ling Li; Hong-Ping He; Shun-Lin Li; Xiao-Jiang Hao
刊名: PLANTA MEDICA
关键词: Cassia occidentalis ; Leguminosae ; cycloartane triterpenoids ; cycloccidentalic acids A and B ; cycloccidentalisides I-V
英文摘要: A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds were elucidated through detailed spectroscopic analyses, including 1D and 2D NMR techniques, and chemical methods. Compounds 2 and 5 showed modest anti-HIV-1 activities with EC50 values of 2.23 mu M and 4.36 mu M, respectively, in comparison to the positive control.
出版日期: 2012-05-01
卷号: 78, 期号:8, 页码:821-827
DOI标识: 10.1055/s-0031-1298376
语种: 英语
ISSN号: 0032-0943
资助信息: This project was supported by grants from the National Natural Science Foundation of China (No. 30760306, 81001462, and 31170332), 973 Program (2009CB522300), Key Scientific and Technological Program of China (2009ZX09501- 029), and Yunnan Provincial Science Foundation (2006C009Z). The authors are grateful to the members of the Analytical Group in the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, for measurements of all spectra.
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/17625
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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