| Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus | |
Tang, Gui-Hua1,2 ; Zhang, Yu1; Gu, Yu-Cheng3; Li, Shi-Fei1,2; Di, Ying-Tong1; Wang, Yue-Hu4; Yang, Cui-Xian5; Zuo, Guo-Ying5; Li, Shun-Lin1; He, Hong-Ping1; Hao, Xiao-Jiang1
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| Corresponding Author | He, HP (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China,hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 2012-05-01 | |
| Source Publication | JOURNAL OF NATURAL PRODUCTS
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| ISSN | 0163-3864 |
| Volume | 75Issue:5Pages:996-1000 |
| Abstract | Trigoflavidols A (1) and B (2), tetranorditerpenoid dimers possessing a rearrangement skeleton with a spiroketal core moiety, and trigoflavidol C (3), a hexanorditerpenoid, have been isolated from Trigonostemon flavidus along with two known compounds. Compounds 1 and 2 showed moderate antimicrobial activities (MIC values: 3.12-6.25 mu g/mL) against Staphylococcus aureus, 8#MRSA, and 82#MRSA, and 1, 2, and 5 showed weak activities (IC50 values: 3.75-28.99 mu M) against various human tumor cell lines. |
| Keyword | Reidioides Chinensis Daphnane Constituents Plant |
| Subject Area | Plant Sciences ; Pharmacology & Pharmacy |
| DOI | 10.1021/np3001128 |
| Indexed By | SCI ; IC |
| Language | 英语 |
| WOS ID | WOS:000304385800022 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/17611 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England 4.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China 5.Chengdu Mil Command, Kunming Gen Hosp, Sch Clin, Res Ctr Nat Med, Kunming 650032, Peoples R China |
| Recommended Citation GB/T 7714 | Tang, Gui-Hua,Zhang, Yu,Gu, Yu-Cheng,et al. Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(5):996-1000. |
| APA | Tang, Gui-Hua.,Zhang, Yu.,Gu, Yu-Cheng.,Li, Shi-Fei.,Di, Ying-Tong.,...&Hao, Xiao-Jiang.(2012).Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus.JOURNAL OF NATURAL PRODUCTS,75(5),996-1000. |
| MLA | Tang, Gui-Hua,et al."Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus".JOURNAL OF NATURAL PRODUCTS 75.5(2012):996-1000. |
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