Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus
Tang, Gui-Hua1,2; Zhang, Yu1; Gu, Yu-Cheng3; Li, Shi-Fei1,2; Di, Ying-Tong1; Wang, Yue-Hu4; Yang, Cui-Xian5; Zuo, Guo-Ying5; Li, Shun-Lin1; He, Hong-Ping1; Hao, Xiao-Jiang1
Corresponding AuthorHe, HP (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China,hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
2012-05-01
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume75Issue:5Pages:996-1000
AbstractTrigoflavidols A (1) and B (2), tetranorditerpenoid dimers possessing a rearrangement skeleton with a spiroketal core moiety, and trigoflavidol C (3), a hexanorditerpenoid, have been isolated from Trigonostemon flavidus along with two known compounds. Compounds 1 and 2 showed moderate antimicrobial activities (MIC values: 3.12-6.25 mu g/mL) against Staphylococcus aureus, 8#MRSA, and 82#MRSA, and 1, 2, and 5 showed weak activities (IC50 values: 3.75-28.99 mu M) against various human tumor cell lines.
KeywordReidioides Chinensis Daphnane Constituents Plant
Subject AreaPlant Sciences ; Pharmacology & Pharmacy
DOI10.1021/np3001128
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000304385800022
Citation statistics
Cited Times:32[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/17611
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
4.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China
5.Chengdu Mil Command, Kunming Gen Hosp, Sch Clin, Res Ctr Nat Med, Kunming 650032, Peoples R China
Recommended Citation
GB/T 7714
Tang, Gui-Hua,Zhang, Yu,Gu, Yu-Cheng,et al. Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(5):996-1000.
APA Tang, Gui-Hua.,Zhang, Yu.,Gu, Yu-Cheng.,Li, Shi-Fei.,Di, Ying-Tong.,...&Hao, Xiao-Jiang.(2012).Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus.JOURNAL OF NATURAL PRODUCTS,75(5),996-1000.
MLA Tang, Gui-Hua,et al."Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus".JOURNAL OF NATURAL PRODUCTS 75.5(2012):996-1000.
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