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题名: Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus
作者: Tang, Gui-Hua1, 2; Zhang, Yu1; Gu, Yu-Cheng3; Li, Shi-Fei1, 2; Di, Ying-Tong1; Wang YueHu(王跃虎)4; Yang, Cui-Xian5; Zuo, Guo-Ying5; Li, Shun-Lin1; He, Hong-Ping1; null(郝小江)1
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: REIDIOIDES ; CHINENSIS ; DAPHNANE ; CONSTITUENTS ; PLANT
英文摘要: Trigoflavidols A (1) and B (2), tetranorditerpenoid dimers possessing a rearrangement skeleton with a spiroketal core moiety, and trigoflavidol C (3), a hexanorditerpenoid, have been isolated from Trigonostemon flavidus along with two known compounds. Compounds 1 and 2 showed moderate antimicrobial activities (MIC values: 3.12-6.25 mu g/mL) against Staphylococcus aureus, 8#MRSA, and 82#MRSA, and 1, 2, and 5 showed weak activities (IC50 values: 3.75-28.99 mu M) against various human tumor cell lines.
出版日期: 2012-05-01
卷号: 75, 期号:5, 页码:996-1000
DOI标识: 10.1021/np3001128
语种: 英语
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/17611
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
4.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China
5.Chengdu Mil Command, Kunming Gen Hosp, Sch Clin, Res Ctr Nat Med, Kunming 650032, Peoples R China

Recommended Citation:
Tang,Gui-Hua;Zhang,Yu;Gu,Yu-Cheng;Li,Shi-Fei;Di,Ying-Tong;Wang,Yue-Hu;Yang,Cui-Xian;Zuo,Guo-Ying;Li,Shun-Lin;He,Hong-Ping;Hao,Xiao-Jiang.Trigoflavidols A-C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus,JOURNAL OF NATURAL PRODUCTS,2012,75(5):996-1000
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