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题名: Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia
作者: Zhao Simeng1, 2; Kuang Bin1, 2; Peng Wenwen1, 2; He Wenjun1; Xu Huimin1, 2; Ji Changjiu1, 2; Han Jing1, 2; Zheng Yuqing1, 2; Song Weiwu1, 2; Tan Ninghu1
刊名: CHINESE JOURNAL OF CHEMISTRY
关键词: cyclopeptide ; traditional Chinese medicine ; chemical constituent
英文摘要: Plant cyclopeptides, cyclic compounds formed mainly by the peptidic bonds of 237 protein and non-protein amino acids (mainly L-amino acids) and found in higher plants, have been attractive for their extensive bioactivities and distinctive molecular architectures. During the last half century's study, about 500 cyclopeptides divided into eight types have been isolated from over 120 species, which belong to over 20 families and 60 genera. Some cyclopeptides showed potential anti-tumor, sedative, immunosuppressive, and uterotonic activities. In the Chinese Pharmacopoeia (CP, 2010 Version), 23 species (14 families, 18 genera) containing cyclopeptides have been recorded in the origins of 24 traditional Chinese medicines (TCMs). Heterophyllin B (64), first reported by us from Pseudostellaria heterophylla in 1993 was cited for the first time in CP as the standard substance of cyclopeptides for quality control. In this review, we highlight the progress in the chemical studies of these cyclopeptide-containing TCMs, in particular recent results in our group's publications.
出版日期: 2012-06-01
卷号: 30, 期号:6, 页码:1213-1225
DOI标识: 10.1002/cjoc.201200508
语种: 英语
ISSN号: 1001-604X
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/17601
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China

Recommended Citation:
Zhao Simeng;Kuang Bin;Peng Wenwen;He Wenjun;Xu Huimin;Ji Changjiu;Han Jing;Zheng Yuqing;Song Weiwu;Tan Ninghu.Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia,CHINESE JOURNAL OF CHEMISTRY,2012,30(6):1213-1225
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