Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia
Tao, Hong-Wen; Hao, Xiao-Jiang2; Liu, Pei-Pei; Zhu, Wei-Ming1
2008-12-01
发表期刊ARCHIVES OF PHARMACAL RESEARCH
ISSN0253-6269
卷号31期号:12页码:1547-1551
摘要A new cytotoxic macrocyclic diterpenoid, euphornin L (1), together with seven known analogues were isolated from the plant Euphorbia helioscopia L. The structure of 1 was elucidated by spectral data and X-ray crystallographic analysis. Euphornin L (1) and euphoscopin F (2) exhibited significant cytotoxicity against HL-60 cell lines with IC(50) values of 2.7 and 9.0 mu M, respectively. The (13)C-NMR data of euphoscopin F (2), epieuphoscopin B (3), euphoscopin B (5), and euphoscopin C (6) were also reported for the first time.
关键词Diterpenoid Euphornin l X-ray Euphorbia Helioscopia l Cytotoxicity
资助信息Chinese National Programs for High Technology Research and Development [2007AA091502, 2007AA09z447]; Shanghai Institute of Materia Medica ; Chinese Academy of Sciences
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/1753
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Ocean Univ China, Sch Med & Pharm, Qingdao 266003, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
推荐引用方式
GB/T 7714
Tao, Hong-Wen,Hao, Xiao-Jiang,Liu, Pei-Pei,et al. Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia[J]. ARCHIVES OF PHARMACAL RESEARCH,2008,31(12):1547-1551.
APA Tao, Hong-Wen,Hao, Xiao-Jiang,Liu, Pei-Pei,&Zhu, Wei-Ming.(2008).Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia.ARCHIVES OF PHARMACAL RESEARCH,31(12),1547-1551.
MLA Tao, Hong-Wen,et al."Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia".ARCHIVES OF PHARMACAL RESEARCH 31.12(2008):1547-1551.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201110260070.pdf(190KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Tao, Hong-Wen]的文章
[Hao, Xiao-Jiang]的文章
[Liu, Pei-Pei]的文章
百度学术
百度学术中相似的文章
[Tao, Hong-Wen]的文章
[Hao, Xiao-Jiang]的文章
[Liu, Pei-Pei]的文章
必应学术
必应学术中相似的文章
[Tao, Hong-Wen]的文章
[Hao, Xiao-Jiang]的文章
[Liu, Pei-Pei]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。