| Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers | |
Gu, Wei1,2 ; Hao, Xiao-Jiang3; Liu, Hong-Xin1,2; Wang, Yue-Hu1; Long, Chun-Lin1,4
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| 通讯作者 | Long,CL (reprint author),Minzu Univ China,Coll Life & Environm Sci,Beijing 100081,Peoples R China.,wangyuehu@mail.kib.ac.cn ; long@mail.kib.ac.cn |
| 2013-11-01 | |
| 发表期刊 | PHYTOCHEMISTRY LETTERS
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| ISSN | 1874-3900 |
| 卷号 | 6期号:4页码:681-685 |
| 摘要 | Nine acylated iridoid glycosides (1-9), five acylated rhamnopyranoses (10-14) and verbascoside (15) were isolated from Gmelina arborea flowers, including 5 new compounds (1, 2, and 10-12). The cytoprotective activity of 11 selected compounds (1-8, 10, 11, and 15) against CCl4-induced cytotoxicity on liver was determined. Compounds 1, 2, 4, 7, 8 and 15 displayed hepatoprotective activity. 6-O-alpha-L-(2 '',3 ''-di-O-trans-p-hydroxycinnamoyl)rhamnopyranosylcatalpol (2) exhibited the most potent cytoprotective effect with an EC50 value of 42.5 mu M (SI = 19.3) compared with biphenyldimethylesterate (DDB, EC50 = 277.3 mu M, SI = 9.8) and bicylo-ethanol (EC50 = 279.2 mu M, SI = 12.2). Among the acylated iridoid glycosides, the compounds (2 and 8) containing phenolic hydroxy groups were more active than were those lacking them. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
| 关键词 | Gmelina Arborea Iridoid Glycosides Acylated Rhamnopyranoses Phenylethanoid Cytoprotective Activity |
| 学科领域 | Biochemistry & Molecular Biology ; Plant Sciences |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000325872700038 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/17435 |
| 专题 | 资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 4.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gu, Wei,Hao, Xiao-Jiang,Liu, Hong-Xin,et al. Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers[J]. PHYTOCHEMISTRY LETTERS,2013,6(4):681-685. |
| APA | Gu, Wei,Hao, Xiao-Jiang,Liu, Hong-Xin,Wang, Yue-Hu,&Long, Chun-Lin.(2013).Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers.PHYTOCHEMISTRY LETTERS,6(4),681-685. |
| MLA | Gu, Wei,et al."Acylated iridoid glycosides and acylated rhamnopyranoses from Gmelina arborea flowers".PHYTOCHEMISTRY LETTERS 6.4(2013):681-685. |
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